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Antikörper Treffer 1
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Name/Antigen KLON WIRT TYP ISOTYP SPEZ. REAKT. FORMAT ANWENDUNG HERSTELLER KAT # MENGE PREIS










Anti-​PB1/BAF180
Rabbit
> sec. Ab
Pab IgG
human
Erklärungen der Abkürzungen ansehen.
antigen affinity purified IPErklärungen der Abkürzungen ansehen. Bethyl
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A301-​590A 100 µl

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349 €
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Anti-PB1/BAF180


The SMARCs (SWI/SNF-​related, matrix-​associated, actin-​dependent regulators of chromatin), and BAFs (BRG1-​associated factors), have been identified as components of the mammalian SWI/SNF-​like chromatin-​remodeling protein complexes. These multi-​protein complexes are proposed to function as ATP-​driven motors that translocate along DNA and destabilize nucleosomal structures to facilitate transcription factor binding. PB1/BAF180 is a component of the SWI/SNF-​B (PBAF) complex. It contains six bromodomains which are defined by a 110 amino-​acid module that interacts with acetylated lysine and is found in many chromatin binding proteins and histone acetyltransferases. PB1/BAF180 has been proposed to function as a tumor suppressor protein. Recently, PB1/BAF180 has been found to play a role in mediating cell cycle arrest in response to DNA damage via the regulation of the tumor suppressor p21. Alternate names for PB1/BAF180 include protein polybromo-​1, polybromo-​1D, BRG1-​associated factor 180, hPB1, and PBRM1.
Immunogen: synthetic peptide. The epitope recognized by A301-​590A maps to a region between residue 1 and 50 of human polybromo 1 (BRG1-​associated factor 180) using the numbering given in entry AAP34197.1 (GeneID 55193).


Datenblatt ansehen

Kat #: A301-590A


Menge:
100 µl

Buy Bulk


Preis:
349 €

UniProt ID: Q86U86 (Protein knowledgebase)

Antikörper-Konjugations-Kits

Schlagworte:
Anti-​PB1, Anti-​PB-​1, Anti-​polybromo 1, Anti-​BAF180, Anti-​BAF-​180, Anti-​BRG1-​associated factor 180., antibody, antibodies, Antikörper

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