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ART NR.: A301-590A-T (10 µl | 10 µg)
A301-590A (100 µl | 100 µg)

Hersteller: Bethyl



Anwendungen: IP

Format: antigen affinity purified

Wirt: Rabbit

Isotyp: IgG

Reaktivität: human (expected: mouse, rat, bovine, dog, horse, rabbit, guinea pig_10141, panda, orangutan, rhesus monkey, chimpanzee, white-tufted-ear marmoset, crab-eating macaque, african elephant, naked mole rat, northern white-cheeked gibbon)

Immunogen: synthetic peptide. The epitope recognized by A301-590A-T maps to a region between residue 1 and 50 of human polybromo 1 (BRG1-associated factor 180) using the numbering given in entry AAP34197.1 (GeneID 55193).

Lagerung: +4°C

Versand: +4°C

UniProt ID: Q86U86 | Suche mit UniProt ID

Gene ID: Gene ID 55193 | Suche mit Gene ID

KEGG ID: K11757 | Suche mit KEGG ID

Schlagworte: Anti-hPB1, Anti-PBRM1, Anti-BAF180, Anti-Polybromo-1D, Anti-Protein polybromo-1, Anti-BRG1-associated factor 180


10 µl (10 µg)

61 €


100 µl (100 µg)

385 €

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Bemerkungen: The SMARCs (SWI/SNF-related, matrix-associated, actin-dependent regulators of chromatin), and BAFs (BRG1-associated factors), have been identified as components of the mammalian SWI/SNF-like chromatin-remodeling protein complexes. These multi-protein complexes are proposed to function as ATP-driven motors that translocate along DNA and destabilize nucleosomal structures to facilitate transcription factor binding. PB1/BAF180 is a component of the SWI/SNF-B (PBAF) complex. It contains six bromodomains which are defined by a 110 amino-acid module that interacts with acetylated lysine and is found in many chromatin binding proteins and histone acetyltransferases. PB1/BAF180 has been proposed to function as a tumor suppressor protein. Recently, PB1/BAF180 has been found to play a role in mediating cell cycle arrest in response to DNA damage via the regulation of the tumor suppressor p21. Alternate names for PB1/BAF180 include protein polybromo-1, polybromo-1D, BRG1-associated factor 180, hPB1, and PBRM1.


PB1/BAF180 Antibody

Rabbit anti-PB1/BAF180 Antibody, Affinity Purified
PB1/BAF180 Antibody

Gene and Protein Information


Wurster AL et al., NF-?B and BRG1 bind a distal regulatory element in the IL-3/GM-CSF locus. Mol Immunol. 2011 Sep;48(15-16):2178-88. ChIP
PubMed: 21831442

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