34 products were found matching "P3113-06V.100"!

PARP1 is a nuclear DNA-binding zinc finger protein which can exist as a homo- or hetero-dimer, and is strongly activated by DNA strand breaks. This protein involved in chromatin architecture and DNA metabolism, and participates in protein modification to enhance or repress transcription. PARP1 also plays a role in...

The poly (ADP-ribose) polymerase (PARP) is involved in cell recovery from DNA damage, such as methylation of N3-adenine, which activates the base excision repair process. PARP [Poly (ADP-ribose) polymerase] is a 116kD nuclear chromatin-associated enzyme that is cleaved during apoptosis by caspase-3 into a 24kD...

PARP (Poly (ADP-ribose) polymerase) is a 113kD nuclear protein that can exist as a homo- or hetero-dimer. This protein acts as a molecular "nick sensor" and functions in base excision repair, poly(ADP-ribosyl)ation of acceptor proteins involved in chromatin architecture and DNA metabolism and participates in protein...

Alpha-Parvin (parvus [Latin for "small"]-A/ alpha, also actopaxin and PARV-A) is a 53kD member of the parvin family, alpha-actinin superfamily of proteins. It is widely expressed, and participates in actin filament assembly that precedes cell migration. Human PARVA is 372aa in length. It contains two CH/calponin...

The extracellular matrix (ECM) is a complex structure of secreted macromolecules surrounding mammalian organs and tissues. Controlled interactions between cells and the ECM are important in proliferation, migration, survival, polarity and differentiation. Cells contact the ECM primarily through heterodimeric...

PARP, a 116kD nuclear poly (ADP-ribose) polymerase, appears to be involved in DNA repair predominantly in response to environmental stress (1). This protein can be cleaved by many ICE-like caspases in vitro (2,3) and is one of the main cleavage targets of caspase-3 in vivo (4,5). In human PARP, the cleavage occurs...

Applications:, Suitable for use in ELISA, Immunohistochemistry (frozen and paraffin), Immunoprecipitation, and Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:1,000-1:5,000, Immunohistochemistry (paraffin): Requires antigen retrieval using heat treatment prior to staining of...

Poly-(ADP-Ribose) Polymerase (PARP) is a 116kD nuclear protein which is strongly activated by binding to DNA strand breaks. PARP plays a role in DNA repair as well as in other cellular processes, including DNA replication, cell proliferation and differentiation. During apoptosis, ICE family members, such as...

Poly (ADP-Ribose) Polymerase (PARP) is a 116kD nuclear protein which is strongly activated by binding to DNA strand breaks. PARP plays a role in DNA repair as well as in other cellular processes, including DNA replication, cell proliferation and differentiation. During apoptosis, ICE family members, such as...

PARP, a 116kD nuclear poly (ADP-ribose) polymerase, appears to be involved in DNA repair predominantly in response to environmental stress (1). This protein can be cleaved by many ICE-like caspases in vitro (2,3) and is one of the main cleavage targets of caspase-3 in vivo (4,5). In human PARP the cleavage occurs...

PARP, a 116kD nuclear poly (ADPribose) polymerase, appears to be involved in DNA repair predominantly in response to environmental stress. This protein can be cleaved by many ICElike caspases in vitro and is one of the main cleavage targets of caspase-3 in vivo. In human PARP the cleavage occurs between Asp214 and...

PARP, a 116kD nuclear poly (ADPribose) polymerase, appears to be involved in DNA repair predominantly in response to environmental stress (1). This protein can be cleaved by many ICElike caspases in vitro (2,3) and is one of the main cleavage targets of caspase-3 in vivo (4,5). In human PARP the cleavage occurs...