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Anti-P4HB (Protein Disulfide-isomerase, PDI, Prolyl 4-hydroxylase Subunit beta, Cellular Thyroid Hormone-binding Protein, p55, PO4DB, PDIA1, PDI, ERBA2L)

ART NR.: P3122-05G.100 (100 µg)

Hersteller: USBio


Anwendungen: WB, IP

Format: affinity purified

Klon: 11n150

Wirt: Mouse

Isotyp: IgG2A

Reaktivität: human

Immunogen: Recombinant corresponding to aa18-505 from human Protein Disulfide Isomerase/P4HB expressed in CHO cells (P07237).

Lagerung: -20°C

Versand: +4°C

UniProt ID: P07237 | Suche mit UniProt ID

Gene ID: Gene ID 5034 | Suche mit Gene ID

KEGG ID: K09580 | Suche mit KEGG ID

Schlagworte: EC=, Anti-Protein disulfide-isomerase, Anti-Prolyl 4-hydroxylase subunit beta, Anti-Cellular thyroid hormone-binding protein


100 µg

635 €

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Bemerkungen: This multifunctional protein catalyzes the formation, breakage and rearrangement of disulfide bonds. At the cell surface, seems to act as a reductase that cleaves disulfide bonds of proteins attached to the cell. May therefore cause structural modifications of exofacial proteins. Inside the cell, seems to form/rearrange disulfide bonds of nascent proteins. At high concentrations, functions as a chaperone that inhibits aggregation of misfolded proteins. At low concentrations, facilitates aggregation (anti-chaperone activity). May be involved with other chaperones in the structural modification of the TG precursor in hormone biogenesis. Also acts a structural subunit of various enzymes such as prolyl 4-hydroxylase and microsomal triacylglycerol transfer protein MTTP. [The UniProt Consortium]


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