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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
100-401-C87 | 50 µl | - | - |
6 - 10 business days* |
684.00€
|
Anti-NMDA R2B antibody is directed against NMDA R2Bprotein. The antibody was prepared from... more
Product information "Anti-NMDA R2B"
Anti-NMDA R2B antibody is directed against NMDA R2Bprotein. The antibody was prepared from monospecific neat serum. Anti-NMDA R2B antibodies are specific for the ~180kDa NR2B subunit of the NMDA receptor. Anti-NMDA R2B antibodies exhibit no reactivity towards the NR2A and NR2C subunits. Immunolabeling is blocked by pre-adsorption of antibody with the fusion protein used to generate the antibody. Reactivity is expected against mouse and human. Protein function: NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. In concert with DAPK1 at extrasynaptic sites, acts as a central mediator for stroke damage. Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2 influx through them, resulting in an irreversible neuronal death. [The UniProt Consortium]
Keywords: | Anti-NR2B, Anti-GluN2B, Anti-Grin2b, Anti-NMDAR2B, Anti-Glutamate receptor ionotropic, NMDA 2B, Anti-N-methyl D-aspartate receptor subtype 2B, Anti-Glutamate [NMDA] receptor subunit epsilon-2 |
Supplier: | Rockland Immunochemicals |
Supplier-Nr: | 100-401-C87 |
Properties
Application: | WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | rat, mouse, human |
Immunogen: | fusion protein from the C-terminal region of the NR2B subunit. |
Format: | Antiserum |
Database Information
KEGG ID : | K05210 | Matching products |
UniProt ID : | Q00960 | Matching products |
Gene ID | GeneID 24410 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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