Anti-NHERF1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A302-974A-T	10 µl (2 µg)		-		2 - 8 business days*		164.00€
A302-974A	100 µl		-		2 - 8 business days*		588.00€

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Protein function: Scaffold protein that connects plasma membrane proteins with members of the... more

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Product information "Anti-NHERF1"

Protein function: Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for recycling of internalized ADRB2. Was first known to play a role in the regulation of the activity and subcellular location of SLC9A3. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. May enhance Wnt signaling. May participate in HTR4 targeting to microvilli. Involved in the regulation of phosphate reabsorption in the renal proximal tubules. Involved in sperm capacitation. May participate in the regulation of the chloride and bicarbonate homeostasis in spermatozoa. [The UniProt Consortium]

Keywords:	Anti-NHERF, Anti-EBP50, Anti-NHERF-1, Anti-SLC9A3R1, Anti-Regulatory cofactor of Na(+)/H(+) exchanger, Anti-Sodium-hydrogen exchanger regulatory factor 1, Anti-Ezrin-radixin-moesin-binding phosphoprotein 50
Supplier:	Bethyl Laboratories
Supplier-Nr:	A302-974A

Properties

Application:	WB, IP, IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse (Expected: orangutan, gorilla, chimpanzee, chinese hamster)
Immunogen:	synthetic peptide. The epitope recognized by A302-974A maps to a region between residue 275 and 325 of human Sodium/Hydrogen Exchanger Regulatory Factor 1 using the numbering given in entry NP_004243.1 (GeneID 9368).
Format:	Antigen Affinity Purified