5 products were found matching "Cay13754-1"!
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Anti-NF-kappaB (p65) NLS
Item number: Cay13751-1
NF-kappaB p65 is a ubiquitously expressed transcription factor that is a subunit of the NF-kappaB complex and is encoded by the RELA gene in humans. It is composed of an N-terminal Rel homology domain, which contains the nuclear localization signal (NLS), and mediates dimerization, nuclear localization, and DNA and...
| Keywords: | NF-kappaB3, Nuclear Factor-kappaB (p65) Nuclear Localization Signal, Transcription Factor p65 |
| Application: | ICC, IF, IHC, IHC (paraffin), WB |
| Host: | Rabbit |
417.00€
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GW 806742X
Item number: Cay37541-10
GW 806742X is an inhibitor of necroptosis. It binds to mixed lineage kinase domain-like protein (Mlkl, Kd = 9.3 µM for the mouse protein), reducing its association with the cytoplasmic membrane, and decreases necroptosis induced by TNF-alpha, a Smac mimetic, and the caspase inhibitor Q-VD-OPH (Cay-15260) in isolated...
| Keywords: | 3-[[4-[methyl[4-[[[[4-(trifluoromethoxy)phenyl]amino]carbonyl]amino]phenyl]amino]-2-pyrimidinyl]amino]-benzenesulfonamide |
| Application: | Necroptosis inhibitor |
| CAS | 579515-63-2 |
| MW: | 573.5 D |
From 74.00€
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Butaprost (free acid)
Item number: Cay13741-1
Butaprost is an EP2 selective agonist which has frequently been used to pharmacologically define the EP receptor expression profile of various human and animal tissues and cells. Prostaglandin free acids generally bind to their cognate receptors with 10 to 100 times the affinity of the corresponding ester...
| Keywords: | (±)-15-deoxy-16S-hydroxy-17-cyclobutyl PGE1, 15-deoxy-16S-hydroxy-17-cyclobutyl PGE1,... |
| Application: | EP2 receptor agonist |
| CAS | 433219-55-7 |
| MW: | 394.6 D |
From 142.00€
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Aurora Kinase Inhibitor II
Item number: Cay17541-1
The Aurora kinases are a family of serine/threonine kinases that are key regulators of mitosis and cytokinesis. Aurora kinase inhibitor II is a cell-permeable anilinoquinazoline that blocks the activity of Aurora A (IC50 = 0.39 µM). In MCF-7 cells, it blocks proliferation with an IC50 value of 1.25 µM.Formal Name:...
| Keywords: | 4-(4'-Benzamidoanilino)-6,7-dimethoxyquinazoline, N-[4-[(6,7-dimethoxy-4-quinazolinyl)amino]phenyl]-benzamide |
| Application: | AURKA inhibitor |
| CAS | 331770-21-9 |
| MW: | 400.4 D |
From 84.00€
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(R)-Butaprost
Item number: Cay13745-5
Butaprost is a structural analog of prostaglandin E2 (PGE2) with good selectivity for the EP2 receptor subtype. Butaprost has frequently been used to pharmacologically define the EP receptor expression profile of various human and animal tissues and cells. Serious confusion as to the structure of butaprost was...
| Keywords: | (±)-15-deoxy-16R-hydroxy-17-cyclobutyl PGE1 methyl ester, 15-deoxy-16R-hydroxy-17-cyclobutyl PGE1 methyl ester, TR 4978,... |
| Application: | Bioactive lipid assays |
| CAS | 69648-38-0 |
| MW: | 408.6 D |
From 181.00€
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