Anti-NEDD4L (IHC)

Anti-NEDD4L (IHC)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
IHC-00713-T 10 µl (2500 ng) -

2 - 8 business days*

164.00€
IHC-00713 100 µl (25 µg) -

2 - 8 business days*

623.00€
 
Protein function: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2... more
Product information "Anti-NEDD4L (IHC)"
Protein function: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Inhibits TGF-beta signaling by triggering SMAD2 and TGFBR1 ubiquitination and proteasome-dependent degradation. Promotes ubiquitination and internalization of various plasma membrane channels such as ENaC, Nav1.2, Nav1.3, Nav1.5, Nav1.7, Nav1.8, Kv1.3, EAAT1 or CLC5. Promotes ubiquitination and degradation of SGK1 and TNK2. Ubiquitinates BRAT1 and this ubiquitination is enhanced in the presence of NDFIP1 (PubMed:25631046). Plays a role in dendrite formation by melanocytes (PubMed:23999003). [The UniProt Consortium]
Keywords: Anti-NEDD4L, Anti-Nedd4-2, Anti-NEDD4.2, Anti-KIAA0439, EC=2.3.2.26, Anti-E3 ubiquitin-protein ligase NEDD4-like, Anti-HECT-type E3 ubiquitin transferase NED4L
Supplier: Bethyl Laboratories
Supplier-Nr: IHC-00713

Properties

Application: IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse (Expected: rat, bovine, dog, horse, guinea pig_10141, pig, panda, orangutan, monkey, gorilla, chimpanzee, zebra finch, naked mole rat)
Immunogen: synthetic peptide
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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