Anti-NEDD4L, ID (NEDD4L, KIAA0439, NEDL3, E3 ubiquitin-protein ligase NEDD4-like, NEDD4.2, Nedd4-2)

Anti-NEDD4L, ID (NEDD4L, KIAA0439, NEDL3, E3 ubiquitin-protein ligase NEDD4-like, NEDD4.2, Nedd4-2)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
038877-HRP.200 200 µl - -

3 - 19 business days*

993.00€
 
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in... more
Product information "Anti-NEDD4L, ID (NEDD4L, KIAA0439, NEDL3, E3 ubiquitin-protein ligase NEDD4-like, NEDD4.2, Nedd4-2)"
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Inhibits TGF-beta signaling by triggering SMAD2 and TGFR1 ubiquitination and proteasome-dependent degradation. Promotes ubiquitination and internalization of various plasma membrane channels such as ENaC, Nav1.2, Nav1.3, Nav1.5, Nav1.7, Nav1.8, Kv1.3, EAAT1 or CLC5. Promotes ubiquitination and degradation of SGK. Applications: Suitable for use in Western Blot, ELISA, Recommended Dilution: ELISA: 1:1,000, Western Blot: 1:100-500, Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. , , Note: Applications are based on unconjugated antibody.
Keywords: Anti-NEDD4L, Anti-Nedd4-2, Anti-NEDD4.2, Anti-KIAA0439, EC=6.3.2.-, Anti-E3 ubiquitin-protein ligase NEDD4-like
Supplier: United States Biological
Supplier-Nr: 038877-HRP

Properties

Application: ELISA, WB
Antibody Type: Polyclonal
Conjugate: HRP
Host: Rabbit
Species reactivity: mouse
Immunogen: NEDD4L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 575-604 amino acids from the Central region of human NEDD4L.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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