- Search results for IHC-00575
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27 products were found matching "IHC-00575"!
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Item number: IHC-00572
Protein function: Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of...
Keywords: | Anti-SCG2, Anti-MEN1, Anti-Menin |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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Item number: IHC-00570
Protein function: Serine/threonine-protein kinase that converts transient diacylglycerol (DAG) signals into prolonged physiological effects downstream of PKC, and is involved in the regulation of cell proliferation via MAPK1/3 (ERK1/2) signaling, oxidative stress- induced NF-kappa-B activation, inhibition of HDAC7...
Keywords: | Anti-PKD2, Anti-PRKD2, Anti-HSPC187, Anti-nPKC-D2, EC=2.7.11.13, Anti-Serine/threonine-protein kinase D2 |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: IHC-00571
Protein function: Acts in a Rho-dependent manner to recruit PFY1 to the membrane. Required for the assembly of F-actin structures, such as actin cables and stress fibers. Nucleates actin filaments. Binds to the barbed end of the actin filament and slows down actin polymerization and depolymerization. Required for...
Keywords: | Anti-DRF1, Anti-DIAP1, Anti-DIAPH1, Anti-Diaphanous-related formin-1, Anti-Protein diaphanous homolog 1 |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: IHC-00573
Protein function: Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II and is implicated in regulation of development and maintenance of embryonic stem cell pluripotency. PAF1C associates with RNA polymerase II through interaction with POLR2A CTD non-...
Keywords: | Anti-RDL, Anti-LEO1, Anti-RNA polymerase-associated protein LEO1, Anti-Replicative senescence down-regulated leo1-like... |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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Item number: IHC-00574
Protein function: RNA-binding protein that plays a central role in myelinization (PubMed:16641098). Binds to the 5'-NACUAAY-N(1,20)- UAAY-3' RNA core sequence. Regulates target mRNA stability (PubMed:23630077). In addition, acts by regulating pre-mRNA splicing, mRNA export and protein translation. Required to...
Keywords: | Anti-QKI, Anti-Hqk, Anti-HKQ, Anti-HqkI, Anti-Protein quaking |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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Item number: IHC-00576
Protein function: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'- CCAAT-3' box motif found in the promoters of its target genes. NF- Y can function as both an activator and a repressor, depending on its interacting cofactors. NF-YA positively...
Keywords: | Anti-NFYA, Anti-NF-YA, Anti-CAAT box DNA-binding protein subunit A, Anti-Nuclear transcription factor Y subunit A,... |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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Item number: IHC-00577
Protein function: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'- CCAAT-3' box motif found in the promoters of its target genes. NF- Y can function as both an activator and a repressor, depending on its interacting cofactors. [The UniProt Consortium]
Keywords: | Anti-NFYC, Anti-NF-YC, Anti-Transactivator HSM-1/2, Anti-CAAT box DNA-binding protein subunit C, Anti-Nuclear... |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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Item number: IHC-00578
Protein function: Recruited and tyrosine phosphorylated by several receptor systems, for example the T-cell, leptin and insulin receptors. Once phosphorylated, functions as an adapter protein in signal transduction cascades by binding to SH2 and SH3 domain- containing proteins. Role in G2-M progression in the cell...
Keywords: | Anti-p68, Anti-Sam68, Anti-Src-associated in mitosis 68 kDa protein, Anti-GAP-associated tyrosine phosphoprotein p62,... |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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Item number: IHC-00579
Protein function: Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF- 2 complex, it binds methionyl-tRNAi to 40 S subunits in a codon- dependent manner, whereas the eIF-2 complex...
Keywords: | Anti-CDA02, Anti-EIF2A |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: 030575.100
PTEN (phosphatase and tensin homolog) was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. This protein is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity...
Keywords: | Anti-PTEN, Anti-MMAC1, EC=3.1.3.67, EC=3.1.3.48, EC=3.1.3.16, Anti-Phosphatase and tensin homolog, Anti-Mutated in... |
Application: | ELISA, FC, ICC, IF, WB |
Host: | Mouse |
Species reactivity: | human, mouse |
682.00€
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Item number: IHC-00375
Protein function: Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly (PubMed:27362226). Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the chromosome surface (PubMed:27362226)....
Keywords: | Anti-Antigen Ki67 homolog, Anti-Antigen KI-67 homolog, Anti-Proliferation marker protein Ki-67, Anti-Antigen identified by... |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | mouse |
From 164.00€
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Item number: AG-20B-0057-C100
Recognizes the p18 subunit of human caspase-8. Liquid. Purified from concentrated hybridoma tissue culture supernatant. Procaspase-8 belongs to the family of caspases. Binding of FasL to Fas leads to formation of a receptor complex at the cellular membrane, which was named DISC. The DISC consists of oligomerized...
Keywords: | Anti-Casp-8, Anti-CAP4, Anti-FADD-like ICE, EC=3.4.22.61 |
Application: | ICC, IP, WB |
Host: | mouse |
Species reactivity: | human |
From 264.00€
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