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Item number: Cay33335-10

AG-556 is a tyrphostin inhibitor of EGFR (IC50 = 5 µM). It is selective for EGFR over HER2 (IC50 = >500 µM). AG-556 inhibits EGF-induced growth of HER14 cells (IC50 = 3 µM). It inhibits hydrogen peroxide-induced increases in intracellular calcium in HEK293 cells expressing human transient receptor potential...

Keywords:	Tyrphostin 56, Tyrphostin AG-556, (2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(4-phenylbutyl)-2-propenamide
Application:	EGFR inhibitor
CAS	133550-41-1
MW:	336.4 D

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