6 products were found matching "Cay13847-1"!
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GANT 61
Item number: Cay13841-10
Hedgehog proteins, important regulators of development, bind the cell-surface protein Patched, allowing activation of Smoothened. In vertebrates, this ultimately leads to the activation of the zinc-finger transcription factors of the Gli family. Overactivation of this pathway contributes to certain cancers,...
| Keywords: | NSC 136476, 2,2'-[[dihydro-2-(4-pyridinyl)-1,3(2H,4H)-pyrimidinediyl]bis(methylene)]bis(N,N-dimethyl-benzenamine) |
| Application: | GLI antagonist |
| CAS | 500579-04-4 |
| MW: | 429.6 D |
From 109.00€
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TAK-242
Item number: Cay13871-1
TAK-242 is an antagonist of toll-like receptor 4 (TLR4) with an IC50 value of 0.68 µM in a secreted alkaline phosphatase (SEAP) assay. It selectively binds to TLR4 over TLR1-3 and TLR5-10 when used at a concentration of 100 nM. TAK-242 (1 µM) prevents the interaction of TLR4 with its adaptor proteins TIRAP or TRAM...
| Keywords: | Resatorvid, 6R-[[(2-chloro-4-fluorophenyl)amino]sulfonyl]-1-cyclohexene-1-carboxylic acid, ethyl ester |
| Application: | TLR4 adaptor binding inhibitor |
| CAS | 243984-11-4 |
| MW: | 361.8 D |
From 98.00€
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Rabbit Anti-S tag IgG:Biotin
Item number: Cay13471-1
Rabbit anti-S tag IgG conjugated to Biotin Antibody: Rabbit polyclonal anti-S-tag Binding Moiety: Biotin Uses: ELISA, microscropy, and Western blot detection Reactivity: S-tagged proteins Immunogen: KETAAAKFERQHMDS Recommended dilution of 1:500 - 1:10,000. Starting dilution: 1:2,000.Immunogen: KETAAAKFERQHMDS....
| Application: | WB |
| Host: | Rabbit |
| Species reactivity: | broad |
488.00€
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Rp-2'-O-Methylcytidine-5'-O-(1-thiotriphosphate) (sodium...
Item number: Cay38471-2.6
Rp-2'-O-Methylcytidine-5'-O-(1-thiotriphosphate) (Rp-2'-O-methyl-CTP-alpha-S) is an isomer of the sulfur-containing nucleotide derivative 2'-O-methyl-CTP-alpha-S.Formal Name: 2'-O-methyl-cytidine, 5'->P''-ester with [P''(R)]-thiotriphosphoric acid ((HO)2P(O)OP(O)(OH)OP(O)(OH)(SH)), tetrasodium salt. Synonyms:...
| Keywords: | Rp-2'-O-methyl-CTP-alpha-S, 2'-O-methyl-cytidine, 5'->P''-ester with [P''(R)]-thiotriphosphoric acid... |
| Application: | 2'-O-methyl-CTP-alpha-S isomer |
| MW: | 601.2 D |
450.00€
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Tenofovir
Item number: Cay13874-5
Tenofovir is an analog of adenosine monophosphate that has antiviral activity. It is converted by cellular enzymes to tenofovir diphosphate, an obligate chain terminator that inhibits the activity of HIV reverse transcriptase and hepatitis B virus polymerase. Tenofovir diphosphate is a weak inhibitor of mammalian...
| Keywords: | (R)-PMPA, GS-1275, GS-1278, TDF, P-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-phosphonic acid |
| Application: | Antiviral, Reverse transcriptase inhibitor |
| CAS | 147127-20-6 |
| MW: | 287.2 D |
From 109.00€
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AZD 8186
Item number: Cay17384-5
AZD 8186 is a selective PI3Kbeta/delta inhibitor that exhibits IC50 values of 3, 17, and 752 nM for PI3Kbeta, delta, and alpha, respectively, in cells sensitive to isoform-specific PI3K inhibition. It shows no significant binding against a panel of 442 other kinases when tested at a concentration of 10 µM and...
| Keywords: | 8-[(1R)-1-[(3,5-difluorophenyl)amino]ethyl]-N,N-dimethyl-2-(4-morpholinyl)-4-oxo-4H-1-benzopyran-6-carboxamide |
| Application: | PI3Kbeta/delta inhibitor |
| CAS | 1627494-13-6 |
| MW: | 457.5 D |
From 43.00€
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