- Search results for Cay13846-1
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6 products were found matching "Cay13846-1"!
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Item number: Cay13841-10
Hedgehog proteins, important regulators of development, bind the cell-surface protein Patched, allowing activation of Smoothened. In vertebrates, this ultimately leads to the activation of the zinc-finger transcription factors of the Gli family. Overactivation of this pathway contributes to certain cancers,...
Keywords: | NSC 136476, 2,2'-[[dihydro-2-(4-pyridinyl)-1,3(2H,4H)-pyrimidinediyl]bis(methylene)]bis(N,N-dimethyl-benzenamine) |
Application: | GLI antagonist |
CAS | 500579-04-4 |
MW: | 429.6 D |
From 109.00€
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Item number: Cay18461-10
FGIN-1-27 is an indoleacetamide that acts as a high affinity agonist of the 18 kDa translocator protein (TSPO, previously called the peripheral benzodiazepine receptor) with a Ki value of 5 nM. It can enhance steroidogenesis of neuroactive steroids such as allopregnanolone (Cay-16930). Through this action, FGIN-1-27...
Keywords: | 2-(4-fluorophenyl)-N,N-dihexyl-1H-indole-3-acetamide |
Application: | TSPO agonist |
CAS | 142720-24-9 |
MW: | 436.6 D |
From 50.00€
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Item number: Cay13461-1
Goat anti-GST (Glutathione-S-Transferase) IgG conjugated to Alkaline Phosphatase Antibody: Goat polyclonal anti-GST Enzyme: Alkaline Phosphatase Uses: ELISA and Western blot detection Reactivity: GST-tagged proteins Immunogen: GST from S. japonicum Recommended dilution of 1:500 - 1:10,000. Starting dilution:...
Keywords: | Anti-Glutathione S-transferase |
Application: | WB |
Host: | Goat |
Species reactivity: | broad |
488.00€
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Item number: Cay38461-2.4
2',3'-Dideoxycytidine-5'-O-(1-thiotriphosphate) (ddCTP-alpha-S) is a sulfur-containing nucleoside triphosphate derivative. Thiol-containing dideoxynucleoside triphosphates (alpha-S-ddNTPs) incorporated into allele-specific primers prevent complete digestion by 5'-phosphodiesterase, which allows for alkylation and...
Keywords: | ddCTP-alpha-S, alpha[S]ddCTP, 2',3'-dideoxy-cytidine, 5'->P''-ester with thiotriphosphoric acid... |
Application: | Sulfur-containing nucleoside triphosphate |
MW: | 555.2 D |
477.00€
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Item number: Cay13861-5
Fmoc-Succinimide (Fmoc-OSu) is a mixed carbamate reagent for the selective preparation of N-(9-fluorenylmethoxycarbonyl) derivatives of hydroxyamino acids and hydroxyamino acid esters in high yields. Fmoc-OSu is a more preferable alternative to the use of the chloroformate, Fmoc-Cl, because it eliminates the...
Keywords: | FMOC-OSu, N-(9-Fluorenylmethoxycarbonyloxy)succinimide, 2,5-dioxo-1-pyrrolidinyl 9H-fluoren-9-ylmethyl ester-carbonic acid |
Application: | Chemical synthesis |
CAS | 82911-69-1 |
MW: | 337.3 D |
From 43.00€
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Item number: Cay13864-5
KN-93 is a selective inhibitor of Ca2+/calmodulin-dependent kinase type II (CaMKII), competitively blocking CaM binding to the kinase (Ki = 370 nM). It does not affect the activities of PKA, PKC, MLCK, or Ca2+-phosphodiesterase. It inhibits histamine-induced aminopyrine uptake in parietal cells (IC50 = 300 nM). More...
Keywords: | N-[2-[[[3-(4-chlorophenyl)-2-propen-1-yl]methylamino]methyl]phenyl]-N-(2-hydroxyethyl)-4-methoxy-benzenesulfonamide,... |
Application: | CaMKII inhibitor |
CAS | 1956426-56-4 |
MW: | 537.5 D |
From 143.00€
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