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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
A300-053A-T | 10 µl (10 µg) | - |
2 - 8 business days* |
164.00€
|
|||
A300-053A | 100 µl (100 µg) | - |
2 - 8 business days* |
588.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Required for checkpoint mediated cell cycle arrest in response to DNA damage... more
Product information "Anti-MDC1"
Protein function: Required for checkpoint mediated cell cycle arrest in response to DNA damage within both the S phase and G2/M phases of the cell cycle. May serve as a scaffold for the recruitment of DNA repair and signal transduction proteins to discrete foci of DNA damage marked by 'Ser-139' phosphorylation of histone H2AFX. Also required for downstream events subsequent to the recruitment of these proteins. These include phosphorylation and activation of the ATM, CHEK1 and CHEK2 kinases, and stabilization of TP53 and apoptosis. ATM and CHEK2 may also be activated independently by a parallel pathway mediated by TP53BP1. [The UniProt Consortium]
Keywords: | Anti-MDC1, Anti-KIAA0170, Anti-Nuclear factor with BRCT domains 1, Anti-Mediator of DNA damage checkpoint protein 1 |
Supplier: | Bethyl Laboratories |
Supplier-Nr: | A300-053A |
Properties
Application: | WB, IP, IHC |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human (Expected: chimpanzee) |
Immunogen: | synthetic peptide. The epitope recognized by A300-053A maps to a region between residues 1375 and 1425 of human Mediator of DNA Damage Checkpoint 1 using the numbering given in entry NP_055456.1 (GeneID 9656). |
Format: | Antigen Affinity Purified |
Database Information
KEGG ID : | K20780 | Matching products |
UniProt ID : | Q14676 | Matching products |
Gene ID | GeneID 9656 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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