15 products were found matching "M2749-29"!

MCM2 (Mini chromosome maintenance protein-2), is a protein involved in the control of DNA replication. Applications: Suitable for use in Immunohistochemistry and Western Blot. Other applications have not been tested. Recommended Dilution: Immunohistochemistry (frozen): 1:500-1:1000, , Immunohistochemistry...

MCM-5 (mini chromosome maintenance protein 5), a protein with an important role in the control of DNA replication. It has been reported that immunocytochemical assessment of Mcm5 expression may be of value in improving the accuracy of cervical smear testing for the detection of malignancy. Applications: Suitable for...

Mcl-1 is a member of the Bcl-2 family whose members fall into two groups with opposing functions in apoptosis. Pro-survival family members such as Bcl-2, Bcl-xL and Mcl-1 inhibit apoptosis whereas death-inducing members such as Bax, Bid and Bad have the opposite effect. Mcl-1 is an immediate-early gene activated by...

Myeloid cell leukemia sequence 1 (MCL-1) is an anti-apoptotic member of the Bcl-2 family of proteins, first identified in differentiating ML-1 myeloid cells, and expressed in many different cell lines, tissues and a variety of tumors. The MCL-1 protein, localized to intracellular membranes and particularly...

Mcl-1 is an anti-apoptotic member of the Bcl-2 family originally isolated from the ML-1 human myeloid leukemia cell line during phorbol ester-induced differentiation along the monocyte/macrophage pathway (1). Similar to other Bcl-2 family members, Mcl-1 localizes to the mitochondria (2), interacts with and...

Mcl-1 is an anti-apoptotic member of the Bcl-2 family of proteins. It has a pro-survival role in the early stages of apoptosis, and is thought to prevent cytochrome c release from mitochondria. Mcl-1 is also essential for embryogenesis and for the development and maintenance of B and T lymphocytes. Mcl-1 is a highly...

Mcl-1 (Myeloid cell leukemia-1) is a member of the bcl-2 family. The carboxy terminal of Mcl-1 and bcl-2 share significant sequence homology. Expression of Mcl-1 is increased upon exposure of ML-1 cells to various types of DNA damaging agents (e.g. ionizing radiation, ultraviolet radiation, and alkylating drugs)...

Applications:, Suitable for use in ELISA, Immunofluorescence, Western Blot and Immunohistochemistry. Other applications have not been tested. Recommended Dilutions: Immunohistochemistry: 5ug/ml, Western Blot: 1:500-1:2000, ELISA: 1:10,000-1:50,000, Optimal dilutions to be determined by the researcher. Storage and...

MCM2 (Minichromosome maintenance protein 2, also BM28) is a member of the MCM family of proteins. Although its predicted MW is 102kD, it runs anomalously at 125kD in SDS-PAGE. MCM2 forms a large, 450-600kD prereplication complex with MCM3 through 7 plus HBO1, and associates with the ORC to initiate DNA synthesis....

MCM6 may be involved in the control of a single round of DNA replication during S phase. It binds to chromatin during G1 and detaches from it during S phase as if it licenses the chromatin to replicate. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested....

Initiation of DNA replication is a complex process involving the concerted action of many proteins. The chromosome 7-linked gene referred to by Nakatsuru et al. (1995) as MCM2 has been designated MCM7. The MCM2-7 complex is comprised of 6 subunits, MCM2 through MCM7, and is a ring-shaped heterohexameric ATPase...

Initiation of DNA replication is a complex process involving the concerted action of many proteins. The chromosome 7-linked gene referred to by Nakatsuru et al. (1995) as MCM2 has been designated MCM7. The MCM2-7 complex is comprised of 6 subunits, MCM2 through MCM7, and is a ring-shaped heterohexameric ATPase...