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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
A301-633A-T | 10 µl (2 µg) | - |
2 - 8 business days* |
164.00€
|
|||
A301-633A | 100 µl | - |
2 - 8 business days* |
588.00€
|
Protein function: Binds CpG islands in promoters where the DNA is methylated at position 5 of... more
Product information "Anti-MBD2"
Protein function: Binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binds hemimethylated DNA as well. Recruits histone deacetylases and DNA methyltransferases. Acts as transcriptional repressor and plays a role in gene silencing. Functions as a scaffold protein, targeting GATAD2A and GATAD2B to chromatin to promote repression. May enhance the activation of some unmethylated cAMP-responsive promoters. [The UniProt Consortium]
Keywords: | Anti-MBD2, Anti-DMTase, Anti-Demethylase, Anti-Methyl-CpG-binding protein MBD2, Anti-Methyl-CpG-binding domain protein 2 |
Supplier: | Bethyl Laboratories |
Supplier-Nr: | A301-633A |
Properties
Application: | WB, IP, IHC |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse (Expected: dog, guinea pig, swine, orangutan, rhesus monkey, gorilla, chimpanzee, duckbill platypus, tasmanian devil, white-tufted-ear marmoset, crab-eating macaque, european domestic ferret, northern white-cheeked gibbon) |
Immunogen: | synthetic peptide. The epitope recognized by A301-633A maps to a region between residue 361 to 411 of human methyl-CpG binding domain protein 2 using the numbering given in entry NP_003918.1 (GeneID 8932). |
Format: | Antigen Affinity Purified |
Database Information
KEGG ID : | K11590 | Matching products |
UniProt ID : | Q9UBB5 | Matching products |
Gene ID | GeneID 8932 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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