Antikörper Anti-MAP2K1, NT (Dual Specificity Mitogen-activated Protein Kinase Kinase 1, MAP Kinase Kinase 1, MAPKK 1, ERK Activator Kinase 1, MAPK/ERK Kinase 1, MEK 1, MEK1, PRKMK1)

Antikörper Treffer 1

Rubrik: Modifikation:

Name/Antigen	KLON	WIRT	TYP	ISOTYP	SPEZ. REAKT.	FORMAT	ANWENDUNG	HERSTELLER	KAT #	MENGE	PREIS

Anti-MAP2K1, NT (Dual Specificity Mitogen-activated Protein Kinase Kinase 1, MAP Kinase Kinase 1, MAPKK 1, ERK Activator Kinase 1, MAPK/ERK Kinase 1, MEK 1, MEK1, PRKMK1)		Rabbit > sec. Ab	Pab	IgG	human, mouse	affinity purified	ELISA WB IHC	USBio	M2865-12M.100	100 µg Buy Bulk	417 €
Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Binding of extracellular ligands such as growth factors, cytokines and hormones to their cell-surface receptors activates RAS and this initiates RAF1 activation. RAF1 then further activates the dual-specificity protein kinases MAP2K1/MEK1 and MAP2K2/MEK2. Both MAP2K1/MEK1 and MAP2K2/MEK2 function specifically in the MAPK/ERK cascade, and catalyze the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in the extracellular signal-regulated kinases MAPK3/ERK1 and MAPK1/ERK2, leading to their activation and further transduction of the signal within the MAPK/ERK cascade. Depending on the cellular context, this pathway mediates diverse biological functions such as cell growth, adhesion, survival and differentiation, predominantly through the regulation of transcription, metabolism and cytoskeletal rearrangements. One target of the MAPK/ERK cascade is peroxisome proliferator-activated receptor gamma (PPARG), a nuclear receptor that promotes differentiation and apoptosis. MAP2K1/MEK1 has been shown to export PPARG from the nucleus. The MAPK/ERK cascade is also involved in the regulation of endosomal dynamics, including lysosome processing and endosome cycling through the perinuclear recycling compartment (PNRC), as well as in the fragmentation of the Golgi apparatus during mitosis. [The UniProt Consortium] Immunogen: Synthetic peptide selected from the N-terminal region of human MAP2K1 (KLH). Datenblatt ansehen Kat #: M2865-12M.100 Menge: 100 µg Buy Bulk Preis: 417 € UniProt ID: Q02750 (Protein knowledgebase) Geninformationen: GeneID 5604 Passende, verwandte Produkte Antikörper-Konjugations-Kits Schlagworte: Anti-MKK1, EC=2.7.12.2, Anti-MAPK/ERK kinase 1, Anti-MAP kinase kinase 1, Anti-ERK activator kinase 1, Anti-Dual specificity mitogen-activated protein kinase kinase 1, antibody, antibodies, Antikörper Loading ... zurück							Weitere Produkte für dieses Protein: Antibodies Anti-MAP2K1 ( S221 ), Kat #: WA-AP7960j Anti-MAP2K1 (S218) (Dual Specificity Mitogen-activated Protein Kinase Kinase 1, MAP Kinase Kinase 1, MAPKK 1, ERK Activator Kinase 1, MAPK/ERK Kinase 1, MEK 1, MEK1, PRKMK1), Kat #: M2865-12P.100 Anti-MAP2K1 (S218, 222) (Dual Specificity Mitogen-activated Protein Kinase Kinase 1, MAP Kinase Kinase 1, MAPKK 1, ERK Activator Kinase 1, MAPK/ERK Kinase 1, MEK 1, MEK1, PRKMK1), Kat #: M2865-12T.100 Anti-MAP2K1 (S221) (Dual Specificity Mitogen-activated Protein Kinase Kinase 1, MAP Kinase Kinase 1, MAPKK 1, ERK Activator Kinase 1, MAPK/ERK Kinase 1, MEK 1, MEK1, PRKMK1), Kat #: M2865-12U.100 Anti-MAP2K1 (S297), Kat #: WA-AP7960f Anti-MAP2K1 (S297) (Dual Specificity Mitogen-activated Protein Kinase Kinase 1, MAP Kinase Kinase 1, MAPKK 1, ERK Activator Kinase 1, MAPK/ERK Kinase 1, MEK 1, MEK1, PRKMK1), Kat #: M2865-12R.100 Anti-MAP2K1 (T285), Kat #: WA-AP7960i Anti-MAP2K1 (T285) (Dual Specificity Mitogen-activated Protein Kinase Kinase 1, MAP Kinase Kinase 1, MAPKK 1, ERK Activator Kinase 1, MAPK/ERK Kinase 1, MEK 1, MEK1, PRKMK1), Kat #: M2865-12V.100 Anti-MAP2K1 (T291), Kat #: WA-AP7960e Anti-MAP2K1 (T291) (Dual Specificity Mitogen-activated Protein Kinase Kinase 1, MAP Kinase Kinase 1, MAPKK 1, ERK Activator Kinase 1, MAPK/ERK Kinase 1, MEK 1, MEK1, PRKMK1), Kat #: M2865-12Q.100 more Enzymes & Proteins MEK1 (K97R), Recombinant, Human (Map Kinase Kinase, MAPK Kinase, Erk Kinase 1), Kat #: M2865-06J.100 MEK1, inactive human recombinant protein, GST-tag, Kat #: BPS-40531 siRNA MAP2K1 predesign siRNA, Kat #: WA-RI13154 Plasmids/Vectors Human MAP2K1 cDNA Clone, Kat #: WA-DC14871 Chemicals & More MAP2K1 Over-expression Lysate, Kat #: WA-LY10623a Primers MAP2K1, Human mitogen-activated protein kinase kinase 1, Real Time PCR Primer Set, Kat #: VHPS-5520 MAP2K1, Human mitogen-activated protein kinase kinase 1, Real Time PCR Primer Set, Kat #: VHPS-5521 Peptides MAP2K1 Antibody ( S221 ) Blocking Peptide, Kat #: WA-BP7960j MAP2K1 Antibody (N-term) Blocking Peptide, Kat #: WA-BP7960a MAP2K1 Antibody (S217) Blocking Peptide, Kat #: WA-BP7960d MAP2K1 Antibody (S297) Blocking Peptide, Kat #: WA-BP7960f MAP2K1 Antibody (T285) Blocking Peptide, Kat #: WA-BP7960i MAP2K1 Antibody (T291) Blocking Peptide, Kat #: WA-BP7960e MAP2K1 Antibody (T385) Blocking Peptide, Kat #: WA-BP7960g MEK1 Antibody (Center) Blocking Peptide, Kat #: WA-BP7960c MEK1 Antibody (S217) Blocking Peptide, Kat #: WA-BP7904b MEK1 Antibody (S218/222) Blocking Peptide, Kat #: WA-BP7960h more Relevant Pathways: MAPK signaling pathway ErbB signaling pathway MAPK signaling pathway - fly Chemokine signaling pathway Oocyte meiosis Vascular smooth muscle contraction Dorso-ventral axis formation VEGF signaling pathway Osteoclast differentiation Focal adhesion Gap junction Toll-like receptor signaling pathway Plant-pathogen interaction Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Long-term potentiation Neurotrophin signaling pathway Cholinergic synapse Serotonergic synapse Long-term depression Regulation of actin cytoskeleton Insulin signaling pathway GnRH signaling pathway Progesterone-mediated oocyte maturation Melanogenesis Prion diseases Alcoholism Influenza A Pathways in cancer Colorectal cancer Renal cell carcinoma Pancreatic cancer Endometrial cancer Glioma Prostate cancer Thyroid cancer Melanoma Bladder cancer Chronic myeloid leukemia Acute myeloid leukemia Non-small cell lung cancer Products for: MAP2K1, MEK1 - mitogen-activated protein kinase kinase 1 [EC:2.7.12.2] Antibodies (88) Chemicals & More (20) Enzymes & Proteins (2) Peptides (18) Primers (6)

Datenbank vom 17.05.2013, 09:06 Uhr

Die Preise für Antikörper verstehen sich exkl. Versandkosten, eventuell anfallender Kühlmittelpauschale sowie der jeweils geltenden Mehrwertsteuer.