Anti-MAP Kinase, p38, alpha (MAPK, Erk2, Extracellular Signal Regulated Kinase, RK, CSBP, Mitogen Ac

Anti-MAP Kinase, p38, alpha (MAPK, Erk2, Extracellular Signal Regulated Kinase, RK, CSBP, Mitogen Ac
Item number Size Datasheet Manual SDS Delivery time Quantity Price
M2352-01A.100 100 µl - -

3 - 19 business days*

682.00€
 
P38 MAP kinase (MAPK), also called RK (3) or CSBP (2), is the mammalian homologue of the yeast... more
Product information "Anti-MAP Kinase, p38, alpha (MAPK, Erk2, Extracellular Signal Regulated Kinase, RK, CSBP, Mitogen Ac"
P38 MAP kinase (MAPK), also called RK (3) or CSBP (2), is the mammalian homologue of the yeast HOG kinase and participates in a signaling cascade controlling cellular responses to cytokines and stress (1-4). Four isoforms of p38 MAP kinase, alpha, beta, gamma and delta, have been identified so far. Like the SAPK/JNK pathway, p38 MAP kinase is activated by a variety of cellular stresses including osmotic shock, inflammatory cytokines, lipopolysaccharides (LPS), UV light and growth factors (1-5). MKK3 and SEK activate p38 MAP kinase by phosphorylation at Thr180 and Tyr182. Activated p38 MAP kinase has been shown to phosphorylate and activate MAPKAP kinase 2 (3) and to phosphorylate the transcription factors ATF-2 (5), Max (6) and MEF2 (5-8). Applications: Suitable for use in Western Blot, Immunoprecipitation. Other applications not tested. Recommended Dilution: Western Blot: 1:1000, Immunoprecipitation: 1:100, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-SAPK2a, EC=2.7.11.24, Anti-MAPK 14, Anti-MAP kinase 14, Anti-MAP kinase MXI2, Anti-MAP kinase p38 alpha, Anti-CSAID-binding protein, Anti-MAX-interacting protein 2, Anti-Stress-activated protein kinase 2a
Supplier: United States Biological
Supplier-Nr: M2352-01A

Properties

Application: IP, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, monkey, mouse, rat
MW: 4 kD
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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