- Search results for Cay160250
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23 products were found matching "Cay160250"!
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Item number: Cay16002-500
Sp-8-bromo-cyclic AMPS (Sp-8-bromo-cAMPS) is a cell-permeable, cAMP analog that combines an exocyclic sulfur substitution in the axial position of the cyclophosphate ring with a bromine substitution in the adenine base of cAMP. This configuration pools the structural features of two established cyclic-AMP-dependent...
Keywords: | 8-Bromoadenosine 3',5'-cyclic Monophosphothioate SP-Isomer, Sp-8-bromo-cAMPS,... |
Application: | Cell-permeable, cAMP analog, PKA agonist |
CAS | 1573115-90-8 |
MW: | 446.2 D |
From 158.00€
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Item number: Cay160250-1
Leukotriene A4 hydrolase (LTA4 hydrolase) has been cloned from a variety of species including human, rat, and guinea pig. These species exhibit ~90% homology at the amino acid level. Human LTA4 hydrolase has a calculated molecular mass of 69 kDa based on the deduced amino acid sequence.Synonyms: LTA4 Hydrolase....
Keywords: | Anti-LTA4, Anti-LTA4H, Anti-LTA-4 hydrolase, Anti-LTA-4 hydrolase, Anti-Leukotriene A-4 hydrolase, Anti-Leukotriene A-4... |
Application: | IHC, WB |
Host: | Rabbit |
Species reactivity: | human |
422.00€
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Item number: Cay16025-10
PHTPP is a pyrazolo[1,5-alpha]pyrimidine-based ligand that acts as a full antagonist of estrogen ERbeta receptors with 36-fold selectivity over ERalpha. It exhibits no significant agonism on ERalpha or ERbeta. This compound has been used to selectively target ERbeta in the study of the opposing effects of hormone...
Keywords: | 4-[2-phenyl-5,7-bis(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]-phenol |
Application: | Erbeta antagonist |
CAS | 805239-56-9 |
MW: | 423.3 D |
From 130.00€
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Item number: Cay16026-50
UVI3003 is a full antagonist of RXR that demonstrates potent, nanomolar binding affinity. At 1 µM, UVI3003 does not affect the corepressor interaction capacity of the RARalpha subunit in the RAR-RXR heterodimer configuration. This compound can be used to isolate the contribution of RXR to the function of RXR...
Keywords: | 3-[4-hydroxy-3-[5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-3-(pentyloxy)-2-naphthalenyl]phenyl]-2-propenoic acid |
Application: | RXR antagonist |
CAS | 847239-17-2 |
MW: | 436.6 D |
From 130.00€
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Item number: Cay16024-50
Tomatine is a steroidal saponin that has been found in S. lycopersicum and has diverse biological activities. It is active against a panel of 19 plant pathogenic fungi (EC50s = 13-912 µM) and inhibits the growth of L. amazonensis promastigotes (IC50 = 124 nM). Tomatine (0.75, 1, and 1.5 µM) inhibits autophagy and...
Keywords: | Lycopersicin, NSC 234440, NSC 9223, alpha-Tomatine, (3beta,5alpha,22beta,25S)-spirosolan-3-yl... |
Application: | Bioactive steroidal saponin |
CAS | 17406-45-0 |
MW: | 1034.2 D |
From 77.00€
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Item number: Cay16008-250
L-Leucyl-L-Leucine methyl ester (LLME) is a lysosomal condensation product that has been reported to be cytotoxic towards natural killer cells and CD4+ and CD8+ T lymphocytes without affecting helper T cells and B cells. It has also been shown to induce death of monocytes, polymorphonuclear leukocytes, and myeloid...
Keywords: | LLME, LLOMe, L-leucyl-L-leucine, methyl ester, monohydrochloride |
Application: | Specific cytotoxin |
CAS | 6491-83-4 |
MW: | 294.8 D |
From 43.00€
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Item number: Cay16040-250
Cefotaxime is a cephalosporin antibiotic with potent in vitro activity against streptococcal species, including S. aureus (IC50 = 2 µg/ml) and penicillin-resistant S. pneumoniae. It is also effective against a wide range of other beta-lactamase-producing bacterial species (MIC90s = 0.01 - 130 µg/ml). Cefotaxime acts...
Keywords: | (6R)-3-[(acetyloxy)methyl]-7R-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0... |
Application: | Antibacterial antibiotic, peptidoglycan biosynthesis inhibitor |
CAS | 64485-93-4 |
MW: | 477.5 D |
From 43.00€
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Item number: Cay16089-250
Cholesterol ester storage disease and Wolman disease are recessive autosomal disorders caused by a deficiency in lysosomal acid lipase (LAL), also known as cholesteryl ester hydrolase. 4-Methylumbelliferyl palmitate (4-MUP) is a fluorogenic substrate for lysosomal acid lypase (LAL). 4-MUP is cleaved by LAL to...
Keywords: | 4-MU Palmitate, 4-MUP, Palmitoyl 4-Methylumbelliferone, hexadecanoic acid, 4-methyl-2-oxo-2H-1-benzopyran-7-yl ester |
Application: | Fluorogenic LAL / Cholesteryl esterase substrate |
CAS | 17695-48-6 |
MW: | 414.6 D |
From 104.00€
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Item number: Cay16062-250
Adenosine 2'(3')-monophosphate (mixed isomers) is a mixture of adenosine monophosphate (AMP) derivatives with the phosphate bound at the 2'- or 3'-position as opposed to the 5'-position in AMP. Non-canonical AMP derivatives have been used to study AMP-dependent cellular processes.Formal Name: 2'-adenylic acid,...
Keywords: | 2'(3')-AMP, 2'-adenylic acid, 3'-adenylic acid |
Application: | AMP derivative |
MW: | 347.2 D |
From 76.00€
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Item number: Cay16091-250
Salic acids are nine-carbon carbohydrate alpha-keto acids that have many important biological functions, including cell-cell recognition and host-pathogen interactions. N-Acetylneuraminic acid (NANA) is the most abundant sialic acid and is found in bacteria as well as in eukaryotic cells. The pathways for NANA...
Keywords: | NANA, Neu5Ac, N-acetyl-neuraminic acid |
Application: | Sialic acid |
CAS | 131-48-6 |
MW: | 309.3 D |
From 43.00€
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Item number: Cay16021-250
Ciclopirox is an iron chelator, antifungal, and anticancer agent. It inhibits the iron-dependent enzyme hypoxia-inducible factor prolyl hydroxylase 2 (HIF-PH2, IC50 = 1.58 µM), an effect that is reduced in the presence of iron. It stabilizes hypoxia-inducible factor-alpha (HIF-1alpha) under normoxic conditions in...
Keywords: | HOE 296b, 6-cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridinone |
Application: | Antifungal, Cell-permeable iron-chelating agent, EGLN1 inhibitor |
CAS | 29342-05-0 |
MW: | 207.3 D |
From 109.00€
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Item number: Cay16070-250
Oseltamivir is an antiviral prodrug targeted against the influenza viruses. Once hydrolyzed in the liver to its active metabolite, oseltamivir acid (Cay-15779), it can competitively inhibit viral neuraminidase (IC50s = 0.1-4.9 nM for influenza neuraminidases A and B), blocking the release of new viral particles from...
Keywords: | GS-4104, Ro 64-0796/002, Tamiflu(R), 4R-(acetylamino)-5S-amino-3R-(1-ethylpropoxy)-1-cyclohexene-1-carboxylic acid, ethyl... |
Application: | Antiviral prodrug, influenzavirus A, B neuraminidase inhibitor |
CAS | 204255-11-8 |
MW: | 410.4 D |
From 66.00€
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