Anti-LRRN1 (Leucine-rich Repeats Neuronal Protein 1, Neuronal Leucine-rich Repeat Protein 1, NLRR-1,

LRRN1 is a 95kD member of the neuronal LRR family of proteins. It is a cell-surface glycoprotein that is expressed on embryonic motor neurons and somatic myoblasts. Human LRRN1 is 716aa in length. It is a type I transmembrane protein that contains a 606aa extracellular region aa26-631 and a short 64aa cytoplasmic tail. The extracellular region shows eleven LRRs aa94-384 that mediate protein-protein interactions, one C2-type Ig-like domain and one fibronectin type III domain. There is one potential alternate start site at Met286. Over aa26-631, human LRRN1 shares 96% aa sequence identity with mouse LRRN1. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 0.1ug/ml, Immunohistochemistry: 5-15ug/ml, Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.