49 products were found matching "L2601-06K"!

LRP5 and LRP6 are single-pass transmembrane proteins belonging to the low-density-lipoprotein receptor (LDLR) related protein family. Unlike other members of the LDLR family, LRP5 and LRP6 have four EGF and three LDLR repeats in the extracellular domain and proline-rich motifs in the cytoplasmic domain. They...

LRP6 is essential for the Wnt/beta catenin signaling pathway, probably by acting as a coreceptor together with Frizzled for Wnt. It is a specific, high-affinity receptor for DKK1 and DKK2, but not DKK3. The interaction with DKK1 blocks LRP6-mediated Wnt/beta catenin signaling via LRP6 removal via Kremen...

This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt...

LRP6 (Low-density lipoprotein receptor-related protein 6) is a 200-210kD member of the LDLR family of proteins. It is widely expressed, and serves as a coreceptor for both Wnt and parathyroid hormone. In the Wnt system, LRP6 associates with select Fzd multipass receptors, in the PTH system, LRP6 complexes with...

LDL receptor-related protein1(LRP-1), also known as CD91 and the A2-macroglobulin receptor, is a widely expressed type I transmembrane (TM) protein in the LDL receptor superfamily. LRP-1 is important for the clearance of circulating molecules involved in fatty acid metabolism, inhibition of serine proteases, and...

Applications:, Suitable for use in Western Blot, FACS and Immunofluorescence microscopy. Other applications not tested. Recommended Dilutions: Immunofluorescence microscopy: 1:10-1:50. , Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for...

LDL R is the prototype low density lipoprotein receptor. It is a transmembrane protein that plays a role in cholesterol homeostasis by mediating the uptake of low density lipoproteins. Some of the many allelic variants of LDL R cause familial hypercholesterolemia. Applications: Suitable for use in Flow Cytometry....

The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the...

LDL R is the prototype low density lipoprotein receptor. It is a transmembrane protein that plays a role in cholesterol homeostasis by mediating the uptake of low density lipoproteins. Some of the many allelic variants of LDL R cause familial hypercholesterolemia. Applications: Suitable for use in Flow Cytometry....

Low density lipoprotein (LDL) receptor-related protein (LRP), a member of the LDL receptor family, binds multiple classes of ligands and has been implicated in a broad range of normal and disease processes involving lipid metabolism, protease clearance, and cell migration. Structurally, members of the LDLR family...

The LDL receptor (160kD mature or glycosylated receptor, 120kD precursor or unglycosylated receptor) plays a key role in cellular cholesterol homeostasis. Applications: Suitable for use in Flow Cytometry, Western Blot and Receptor binding studies. Other applications have not been tested. Recommended Dilution: Flow...

The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the...