The LDL Receptor (160kD mature or glycosylated receptor, 120kD precursor or unglycosylated receptor) plays a key role in cellular cholesterol homeostasis. Applications: Suitable for use in ELISA, Western Blot, FACS and Immunohistochemistry. Other applications have not been tested. Recommended Dilution: Western...

WNT proteins have diverse roles in governing cell fate, proliferation, migration, porarity and death. WNT signaling controls development and is important for embryogenesis and carcinogenesis (1-3). WNTs are transduced through at least three distinct intracellular signaling pathways including the canonical...

LRP-5 (low-density lipoprotein receptor-related protein 5) is a 1615aa, 180-200kD type I transmembrane glycoprotein. The 1353aa extracellular domain (ECD) contains 20 class B LDLR, 4 EGF-like, and 3 class A LDLR repeats. Human LRP-5aa 745-1097 encompasses class B LDLR repeats #12-17 and EGF-like repeat #3. It shares...