9 products were found matching "L1565-15D.100"!

Lymphocyte-specific protein-tyrosine kinase (Lck), also known as p56Lck and Lsk, is a member of the Src family of non-receptor tyrosine kinases. First identified as a gene rearranged and overexpressed in murine lymphomas, lck behaves as a proto-oncogene and its activation can lead to cellular transformation. Lck...

Lck, a member of the Src family of protein tyrosine kinases, is essential for T-lymphocyte activation and differentiation (1,2). It is associated with a variety of cell surface receptors and plays a key role in T-cell antigen receptor linked signal transduction pathways. The activity of Lck is regulated by protein...

p56lck is a membrane-associated non-receptor protein tyrosine kinase from the Src family of kinases. The phosphorylation status and the activity of p56lck is regulated by the CD45 tyrosine protein phosphatase. p56lck plays a critical role in T cell development and activation. p56lck gene is localized to a site in...

Lck, a member of the Src family of protein tyrosine kinases, is essential for T-lymphocyte activation and differentiation. It is associated with a variety of cell surface receptors and plays a key role in T-cell antigen receptor linked signal transduction pathways. The activity of Lck is regulated by protein kinases...

Lymphocyte-specific protein-tyrosine kinase (Lck), also known as p56 Lck and Lsk, is a member of the Src family of non-receptor tyrosine kinases. First identified as a gene rearranged and overexpressed in murine lymphomas, lck behaves as a proto-oncogene and its activation can lead to cellular transformation. Lck...

Applications: , Suitable for use in Western Blot and Immunoprecipitation. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C....

Lck is a membrane associated, non-receptor tyrosine kinase belonging to the Src family. It plays a key role in T-cell antigen receptor (TCR)-linked signalling pathways. Lck has also been implicated in JAK and STAT signalling. These signalling pathways are activated in cells over-expressing Lck. Applications:...

This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating...

Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. May also regulate NF-kappa-B, ESR1, NR3C1 and...