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Anti-KDM4A, clone 5H1

ART NR.: Pro-30087 (100 µl)

Hersteller: ProMab

Datenblatt

Anwendungen: WB, IHC, ICC, ELISA

Format: ascites

Klon: 5H1

Wirt: Mouse

Isotyp: IgG1

Reaktivität: human

Immunogen: Purified recombinant fragment of human KDM4A expressed in E. coli.

UniProt ID: O75164
Suche mit UniProt ID

Geninformationen: GeneID 9682

Schlagworte: Anti-KDM4A, Anti-JHDM3A, EC=1.14.11.-, Anti-Lysine-specific demethylase 4A, Anti-Jumonji domain-containing protein 2A, Anti-JmjC domain-containing histone demethylation protein 3A

100 µl

263 €

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Bemerkungen: Ascitic fluid containing 0.03% sodium azide. Protein function: Histone demethylase that specifically demethylates 'Lys- 9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate. Participates in transcriptional repression of ASCL2 and E2F-responsive promoters via the recruitment of histone deacetylases and NCOR1, respectively. [The UniProt Consortium]

Die Preise für Antikörper verstehen sich exkl. Versandkosten, eventuell anfallender Kühlmittelpauschale sowie der jeweils geltenden Mehrwertsteuer.





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