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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
600-401-CD5 | 100 µg | - | - |
6 - 10 business days* |
684.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Anti-KAT5 Antibody was affinity purified from monospecific antiserum by immunoaffinity... more
Product information "Anti-KAT5"
Anti-KAT5 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Multiple isoforms of KAT5 are known to exist. Protein function: Catalytic subunit of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome-DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. Directly acetylates and activates ATM. Component of a SWR1-like complex that specifically mediates the removal of histone H2A.Z/H2AFZ from the nucleosome. In case of HIV-1 infection, interaction with the viral Tat protein leads to KAT5 polyubiquitination and targets it to degradation. Relieves NR1D2-mediated inhibition of APOC3 expression by acetylating NR1D2. [The UniProt Consortium]
Keywords: | Anti-KAT5, Anti-Tip60, Anti-HTATIP, Anti-Lysine acetyltransferase 5, Anti-cPLA(2)-interacting protein, Anti-HIV-1 Tat interactive protein, Anti-Histone acetyltransferase KAT5, Anti-60 kDa Tat-interactive protein, Anti-Histone acetyltransferase HTATIP |
Supplier: | Rockland Immunochemicals |
Supplier-Nr: | 600-401-CD5 |
Properties
Application: | ELISA, IHC, IFM, WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | 15 amino acid peptide near the C-terminus of human KAT5. |
Format: | Purified |
Database Information
KEGG ID : | K11304 | Matching products |
UniProt ID : | Q92993 | Matching products |
Gene ID | GeneID 10524 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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