Anti-JMY, NT (JMY, Junction-mediating and -regulatory protein) (Azide free) (FITC)

Anti-JMY, NT (JMY, Junction-mediating and -regulatory protein) (Azide free) (FITC)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
037210-FITC.200 200 µl - -

3 - 19 business days*

993.00€
 
JMY acts both as a nuclear p53/TP53-cofactor and a cytoplasmic regulator of actin dynamics... more
Product information "Anti-JMY, NT (JMY, Junction-mediating and -regulatory protein) (Azide free) (FITC)"
JMY acts both as a nuclear p53/TP53-cofactor and a cytoplasmic regulator of actin dynamics depending on conditions. In nucleus, acts as a cofactor that increases p53/TP53 response via its interaction with p300/EP300. Increases p53/TP53-dependent transcription and apoptosis, suggesting an important role in p53/TP53 stress response such as DNA damage. In cytoplasm, acts as a nucleation-promoting factor for both branched and unbranched actin filaments. Activates the Arp2/3 complex to induce branched actin filament networks. Also catalyzes actin polymerization in the absence of Arp2/3, creating unbranched filaments. Contributes to cell motility by controlling actin dynamics. May promote the rapid formation of a branched actin network by first nucleating new mother filaments and then activating Arp2/3 to branch off these filaments. The p53/TP53-cofactor and actin activator activities are regulated via its subcellular location (By similarity). Applications: Suitable for use in Western Blot, FLISA, Recommended Dilution: FLISA: 1:1,000, Western Blot: 1:100-500, Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. , , Note: Applications are based on unconjugated antibody.
Keywords: Anti-JMY, Anti-Junction-mediating and -regulatory protein
Supplier: United States Biological
Supplier-Nr: 037210-FITC

Properties

Application: FLISA, WB
Antibody Type: Polyclonal
Conjugate: FITC
Host: Rabbit
Species reactivity: human
Immunogen: JMY antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-29 amino acids from the N-terminal region of human JMY.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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