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Anti-JMJD2A (IHC)

ART NR.: IHC-00188 (100 µl)

Hersteller: Bethyl

Datenblatt

Anwendungen: IHC

Format: antigen affinity purified

Wirt: Rabbit

Isotyp: IgG

Reaktivität: human

Immunogen: synthetic peptide. The epitope recognized by IHC-00188 maps to a region between residues 350 and 400 of human Jumonji Domain Containing 2A using the numbering given in entry NP_055478.1 (GeneID 9682).

UniProt ID: O75164
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Schlagworte: EC=1.14.11.-, Anti-JMJD2A, Anti-Jumonji Domain Containing 2A, Anti-JHDM3A, Anti-JmjC Domain-Containing Histone Demethylation Protein 3A.

100 µl

401 €

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Bemerkungen: JMJD2A is a member of the jumonji (jmj) domain containing gene family of histone demethylases that plays a role in chromatin regulation and influences transcriptional activation and suppression. Some recently characterized members of the jmj family include JARID1A/RBP2, JARID1C, JMJD1A, JMJD1B, JMJD1C, JMJD2A, JMJD2C and JMJD2D. JMJD2A is a trimethylation-specific demethylase and functions as a transcriptional repressor. JMJD2A interacts with pRb and class one histone deacetylases to mediate repression of E2F-regulated promoters. Alternate names for JMJD2A include JmjC domain-containing histone demethylation protein 3A, jumonji domain containing protein 2A, JMJD2, JHDM3A, and KIAA0677.

Spezifikationen

bethyl_datasheet_parse.php?nr=IHC-00188&ak=1
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