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Item number: Cay29817-10

BHBM is an acylhydrazone with antifungal activity. It is active against C. neoformans in vitro (MIC80 = 1 µg/ml). BHBM (0.25, 1, and 4 µg/ml) inhibits the synthesis of glucosylceramide, which is essential to fungal cell division, in C. neoformans but not J774 murine macrophages. In vivo, BHBM (1.2 mg/kg per day)...

Keywords:	2-methyl-benzoic acid 2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide
Application:	Antifungal acylhydrazone, Glucosylceramide synthesis inhibitor
CAS	302807-84-7
MW:	333.2 D

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