Anti-IRF8

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A304-027A-T	10 µl (10 µg)		-		2 - 8 business days*		164.00€
A304-027A	100 µl (100 µg)		-		2 - 8 business days*		588.00€

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Protein function: Specifically binds to the upstream regulatory region of type I IFN and... more

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Product information "Anti-IRF8"

Protein function: Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)). Plays a regulatory role in cells of the immune system. Involved in CD8(+) dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA- 3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF8 and activation of genes. [The UniProt Consortium]

Keywords:	Anti-Irf8, Anti-ICSBP, Anti-IRF-8, Anti-Icsbp, Anti-Interferon regulatory factor 8, Anti-Interferon consensus sequence-binding protein
Supplier:	Bethyl Laboratories
Supplier-Nr:	A304-027A

Properties

Application:	WB, IP, ChIP-Seq
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	mouse (Expected: rat, chinese hamster)
Immunogen:	synthetic peptide. The epitope recognized by A304-027A maps to a region between residue 200 and 250 of mouse Interferon Regulatory Factor 8 using the numbering given in entry NP_032346.1 (GeneID 15900).
Format:	Antigen Affinity Purified