Anti-IL-33, clone IL33068A

Anti-IL-33, clone IL33068A
%
Item number Size Datasheet Manual SDS Delivery time Quantity Discount Price
AG-20A-0042-C050 50 µg -

3 - 9 business days*

10 %
116.00€
104.40€
AG-20A-0042-C100 100 µg -

3 - 9 business days*

10 %
182.00€
163.80€
 
Recognizes human IL-33. Weakly cross-reacts with mouse IL-33. Liquid. 0.2µm-filtered solution in... more
Product information "Anti-IL-33, clone IL33068A"
Recognizes human IL-33. Weakly cross-reacts with mouse IL-33. Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives. Interleukin-33 (IL-33, HF-NEV, IL-1F11), a member of the IL-1 family of cytokines, is expressed by many cell types following pro-inflammatory stimulation and is thought to be released on cell lysis. The 30kDa human IL33 is converted by CASP1 to a 18kDa protein. IL33 binds to and signals through ST2 (IL1R1) and its stimulation recruits MYD88, IRAK, IRAK4, and TRAF6, followed by phosphorylation of ERK1(MAPK3)/ERK2(MAPK1), p38(MAPK14), and JNK. The ability of IL-33 to target numerous immune cell types, like Th2-like cells, mast cells, and B1 cells, and to induce cytokine and chemokine production underlines its potential in influencing the outcome of a wide range of diseases, such as arthritis, asthma, atopic allergy & anaphylaxis, cardiovascular disease/atherosclerosis, nervous system diseases, and sepsis.
Keywords: Interleukin-33, IL-1F11, NF-HEV
Supplier: AdipoGen Life Sciences
Supplier-Nr: AG-20A-0042

Properties

Application: ELISA, WB
Antibody Type: Monoclonal
Clone: IL33068A
Conjugate: No
Host: Mouse
Species reactivity: human
Immunogen: Recombinant human IL-33.
Format: Purified

Database Information

KEGG ID : K12967 | Matching products
UniProt ID : O95760 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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