- Search results for Cay10011427
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6 products were found matching "Cay10011427"!
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Item number: Cay10011247-5
Cyclin-dependent kinases (CDKs) play a key role in regulating cell division by phosphorylating distinct substrates in different phases of the cell cycle. Cell cycle deregulation in many cancers often results from altered CDK activity. Thus, CDKs are potential pharmacological targets for anticancer agents. CAY10574...
Keywords: | 4-[(3,5-diamino-1H-pyrazol-4-yl)azo]-phenol |
Application: | CDK9 inhibitor |
CAS | 140651-18-9 |
MW: | 218.2 D |
From 34.00€
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Item number: Cay11427-10
diacetoxy Scirpenol is a trichothecene mycotoxin originally isolated from F. equiseti. It is toxic to pigs (LD50 = 0.38 mg/kg, i.v.) and lethal to brine shrimp (LC50 = 0.39 µg/ml). diacetoxy Scirpenol (1 µg/ml) suppresses phagocytosis by, and superoxide production in, isolated mouse macrophages in an S. cerevisiae...
Keywords: | Anguidin, DAS, NSC 141537, NSC 177378, Scirpenetriol 4,15-diacetate,... |
Application: | Plant pathogen studies |
CAS | 2270-40-8 |
MW: | 366.4 D |
From 107.00€
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Item number: Cay10011724-50
Propenyl-L-NIO (hydrochloride) (ENIPO) is a potent, selective inhibitor of iNOS. The Ki values for inhibition of iNOS, nNOS, and eNOS by ENIPO are 17, 10.3 and 58.2 µM, respectively, as determined using initial rate binding kinetics. However, ENIPO is a time-dependent inhibitor that, with longer incubations,...
Keywords: | ENIPO, N5-[(3E)-1-imino-3-pentenyl]-L-ornithine, monohydrochloride |
Application: | iNOS inhibitor |
MW: | 249.7 D |
From 77.00€
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Item number: Cay10011127-1
Thioperamide (maleate) is a selective histamine H3 receptor antagonist that crosses the blood-brain barrier. This compound binds to rat cerebral cortical cells in vitro with a pKi value of 8.4 and inhibits histamine binding in vivo with an ED50 value of 1 mg/kg. At a dose of 5 mg/kg thioperamide (maleate) inhibits...
Keywords: | N-cyclohexyl-4-(1H-imidazol-5-yl)-1-piperidinecarbothioamide, 2Z-butenedioate |
Application: | Histamine H3 receptor antagonist |
CAS | 148440-81-7 |
MW: | 408.5 D |
From 20.00€
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Item number: Cay10011497-100
Dinophysistoxin-1 is a marine toxin produced by dinoflagellates that is known to accumulate in shellfish and cause diarrheic shellfish poisoning. It inhibits serine/threonine protein phosphatases 1 (PP1) and PP2A (IC50 = 0.104 nM) and has been shown to promote cancer cell growth in tumor cell lines and animal...
Keywords: | 3-methyl Okadaic Acid, DTX1,... |
Application: | Serine/threonine protein phosphatases 1 (PP1) & PP2A inhibitor |
CAS | 81720-10-7 |
MW: | 819 D |
667.00€
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Item number: Cay10017-10
Ac-DEVD-CHO is a potent inhibitor of the Group II caspases, caspase-3 and caspase-7 (Kis = 0.23 and 1.6 nM, respectively). Notably, it also inhibits other caspases (Kis = 18, 1710, 132, 205, 31, 0.92, 60, and 12 nM for caspases-1, -2, -4, -5, -6, -8, -9, and -10, respectively). Caspase inhibitors in the aldehyde...
Keywords: | N-Ac-Asp-Glu-Val-Asp-CHO, N-acetyl-L-alpha-aspartyl-L-alpha-glutamyl-N-(2-carboxyl-1-formylethyl)-L-valinamide,... |
Application: | Caspase-3 inhibitor |
MW: | 502.5 D |
From 61.00€
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