Anti-Hsp90 alpha, clone Hyb-K41009

Anti-Hsp90? Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Hsp90 from Human (alpha-specific) sources based on 100% homology with the immunizing sequence. Cross-reactivity with Hsp90 from other sources has not been determined. Heat Shock research. Protein function: Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. [The UniProt Consortium]