Acetylation and deacetylation of core histone lysine residues, by histone acetyltransferases (HAT) and histone deacetylases (HDAC) respectively, have been shown to be necessary for some crucial nuclear events such as gene transcription, DNA replication and repair. HDACs are found in multi-protein complexes with...

Histone deacetylase 2 (HDAC2), or transcriptional regulator homolog RPD3 L1, is highly homologous to the yeast transcription factor RPD3 (reduced potassium dependency 3) gene. As in yeast, human HDA2 is likely to be involved in regulating chromatin structure during transcription. It has been implicated to associate...

Applications: , Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:500-1:1000, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are...