Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Probably participates in the regulation of transcription through its binding to the zinc-finger transcription factor YY1. increases YY1 repression activity. Required to repress transcription of the POU1F1 transcription factor. Acts as a molecular chaperone for shuttling phosphorylated NR2C1 to PML bodies for sumoylation (By similarity). [The UniProt Consortium]
Immunogen: Synthetic peptide selected from the C-terminal region of human HDAC3 (KLH).
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Kat #: H1827-55H.100
Menge: 100 µgBuy Bulk
Preis: 417 €
UniProt ID: O15379 (Protein knowledgebase)
Geninformationen: GeneID 8841
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EC=3.5.1.98, Anti-Histone deacetylase 3, antibody, antibodies, Antikörper Loading ...
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Products for: HDAC3 - histone deacetylase 3 [EC:3.5.1.98]
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