Anti-HDAC2

Anti-HDAC2
Item number Size Datasheet Manual SDS Delivery time Quantity Price
600-401-J19 100 µg - -

6 - 10 business days*

684.00€
 
Anti-HDAC2 was affinity purified from monospecific antiserum by immunoaffinity chromatography.... more
Product information "Anti-HDAC2"
Anti-HDAC2 was affinity purified from monospecific antiserum by immunoaffinity chromatography. This antibody is specific towards HDAC2. A BLAST analysis was used to suggest cross-reactivity with Human, Mouse, Rat, and Primate based on 100% sequence homology. Cross-reactivity with HDAC2 from other sources has not been determined. Protein function: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Forms transcriptional repressor complexes by associating with MAD, SIN3, YY1 and N-COR. Interacts in the late S-phase of DNA-replication with DNMT1 in the other transcriptional repressor complex composed of DNMT1, DMAP1, PCNA, CAF1. Deacetylates TSHZ3 and regulates its transcriptional repressor activity. Component of a RCOR/GFI/KDM1A/HDAC complex that suppresses, via histone deacetylase (HDAC) recruitment, a number of genes implicated in multilineage blood cell development. [The UniProt Consortium]
Keywords: Anti-HD2, Anti-HDAC2, EC=3.5.1.98, Anti-Histone deacetylase 2
Supplier: Rockland Immunochemicals
Supplier-Nr: 600-401-J19

Properties

Application: ELISA, IHC, IFM, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat, primates
Immunogen: synthetic peptide corresponding to the C-terminus region of human HDAC2.
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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