56 products were found matching "H1827-51J"!

Histone deacetylase 1 (HDAC1), is responsible for the deacetylation of lysine residues on the N-terminal portion of core histones H2A, H2B, H3, and H4. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression, and developmental...

Human HDAC4 (GenBank Accession No. NM_006037), amino acids 627-1085 with N-terminal GST tag. Specific Activity: ~14,000pmol/min/ug, Assay Condition: 25mM Tris/Cl, pH 8.0, 137mM sodium chloride, 2.7mM KCl, 1mM MgCl2, and 0.1mg/ml BSA, 20uM BPS HDAC substrate, 0.1ng/ul HDAC4. Incubation condition: 30 minutes at...

HDAC11 is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone...

Histone deacetylase 1 (HDAC1), is responsible for the deacetylation of lysine residues on the N-terminal portion of core histones H2A, H2B, H3, and H4. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression, and developmental...

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase/acuc/apha family....

Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient (1). They are present in the membranes that surround all biological cells because their main function is...

Histone deacetylase (HDAC) and histone acetyltransferase (HAT) are enzymes that regulate transcription by selectively deacetylating or acetylating the eta-amino groups of lysines located near the amino termini of core histone proteins (1). Eight members of HDAC family have been identified in the past several years...

Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. HDAC1 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein...

Histone deacetylase 1 (HDAC1), is responsible for the deacetylation of lysine residues on the N-terminal portion of core histones H2A, H2B, H3, and H4. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression, and developmental...

Acetylation of the histone tail causes chromatin to adopt an "open" conformation, allowing increased accessibility of transcription factors to DNA. The identification of histone acetyltransferases (HATs) and their large multiprotein complexes has yielded important insights into how these enzymes regulate...

Human, recombinant, full length with C-terminal His tag expressed in Sf9 cells. Applications: Suitable for use in enzyme kinetics, screening inhibitors and selectivity profiling. Other applications not tested. Specific Activity: ~400pmol/min/ug, Recommended Dilution: Assay Conditions: , 50mM Tris-HCl, pH 8.0, 137mM...

Acetylation of the histone tail causes chromatin to adopt an "open" conformation, allowing increased accessibility of transcription factors to DNA. The identification of histone acetyltransferases (HATs) and their large multiprotein complexes has yielded important insights into how these enzymes regulate...