Anti-FRAP1 (S2481) (Serine/Threonine-protein Kinase mTOR, Mechanistic Target Of Rapamycin, FK506-bin

Anti-FRAP1 (S2481) (Serine/Threonine-protein Kinase mTOR, Mechanistic Target Of Rapamycin, FK506-bin
Item number Size Datasheet Manual SDS Delivery time Quantity Price
F4150-34F-HRP.200 200 µl - -

3 - 19 business days*

993.00€
 
FRAP1 belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate... more
Product information "Anti-FRAP1 (S2481) (Serine/Threonine-protein Kinase mTOR, Mechanistic Target Of Rapamycin, FK506-bin"
FRAP1 belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. FRAP1 is a part of the TORC2 complex which plays a critical role in AKT1 Ser-473 phosphorylation, and may modulate the phosphorylation of PKCA and regulate actin cytoskeleton organization. Applications: Suitable for use in ELISA, Western Blot, and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:1,000, Western Blot: 1:50-1:100, Immunohistochemistry: 1:10-1:50, Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. , , Note: Applications are based on unconjugated antibody.
Keywords: Anti-MTOR, Anti-mTOR, Anti-FRAP, EC=2.7.11.1, Anti-Rapamycin target protein 1, Anti-Rapamycin and FKBP12 target 1, Anti-Mammalian target of rapamycin, Anti-Mechanistic target of rapamycin, Anti-Serine/threonine-protein kinase mTOR
Supplier: United States Biological
Supplier-Nr: F4150-34F-HRP

Properties

Application: ELISA, IHC, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Synthetic non-phosphopeptide corresponding to amino acid residues surrounding S2481 of human FRAP1 (KLH).
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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