Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro). Immunogen: synthetic peptide
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Kat #: ABD-8C0355.50
Menge: 50 µgBuy Bulk
Preis: 195 €
UniProt ID: P25445 (Protein knowledgebase) Geninformationen: GeneID 355
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Antikörper-Konjugations-Kits
Schlagworte: Anti-FAS, Anti-CD95, Anti-APT1, Anti-Apo-1 antigen, Anti-FASLG receptor, Anti-Apoptosis-mediating surface antigen FAS, Anti-Tumor necrosis factor receptor superfamily member 6, antibody, antibodies, Antikörper Loading ...
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Enzymes & Proteins
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siRNA
Plasmids/Vectors
Primers
Peptides
Products for: TNFRSF6, FAS - tumor necrosis factor receptor superfamily member 6
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