- Search results for IHC-00427
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15 products were found matching "IHC-00427"!
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Item number: IHC-00742-T
Protein function: Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. Participates in AID/AICDA-mediated Ig class switching recombination (CSR). May induce apoptosis. [The UniProt Consortium]
Keywords: | Anti-NAP, Anti-PP8304, Anti-CTNNBL1, Anti-C20orf33, Anti-Nuclear-associated protein, Anti-Beta-catenin-like protein 1,... |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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Item number: IHC-00247-T
Protein function: Component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Required for anchoring centrosomal pericentrin in both interphase and mitosis, for spindle organization and centrosome integrity. [The UniProt Consortium]
Keywords: | Anti-hZFH, Anti-CHD3, Anti-CHD-3, Anti-Mi2-alpha, EC=3.6.4.12, Anti-Zinc finger helicase, Anti-ATP-dependent helicase... |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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Item number: IHC-00274-T
Protein function: May be a transcription regulator involved in cell-cycle progression and skeletal muscle differentiation. May repress GTF2I transcriptional functions, by preventing its nuclear residency, or by inhibiting its transcriptional activation. May contribute to slow-twitch fiber type specificity during...
Keywords: | Anti-CREAM1, Anti-GTF2IRD1, Anti-MusTRD1/BEN, Anti-USE B1-binding protein, Anti-General transcription factor III,... |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: AG-20B-0042-C100
Recognizes endogenous full-length and activated (p20 fragment) mouse caspase-1. Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and IL-18 and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called Inflammasomes in response...
Keywords: | Anti-CASP1, Anti-CASP-1, Anti-ICE, EC=3.4.22.36 |
Application: | WB, IHC, IP |
Host: | Mouse |
Species reactivity: | mouse |
440.00€
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Item number: IHC-00422
Protein function: As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA...
Keywords: | Anti-phospho-RPA2, Anti-phospho-REPA2, Anti-phospho-RP-A p34, Anti-phospho-RP-A p32, Anti-phospho-RF-A protein 2,... |
Application: | IHC, IHC-IF |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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Item number: 030427.100
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of...
Keywords: | Anti-ERT2, Anti-ERK1, Anti-MAPK3, Anti-ERK-1, Anti-MAPK 3, Anti-p44-ERK1, Anti-p44-MAPK, Anti-MAP kinase 3, EC=2.7.11.24,... |
Application: | ELISA, FC, IHC, WB |
Host: | Mouse |
Species reactivity: | human, monkey, mouse, rat |
719.00€
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Item number: IHC-00429
Protein function: Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient- insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by...
Keywords: | Anti-hAVO3, Anti-AVO3 homolog, Anti-Rapamycin-insensitive companion of mTOR |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: IHC-00420
Protein function: Ubiquitin: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a...
Keywords: | Anti-UBA52, Anti-UBCEP2 |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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Item number: IHC-00423
Protein function: Plays a role in maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a histone deacetylase-dependent manner, and thus the regulation of E-cadherin levels. Contributes to transcriptional repression by BCL6. [The UniProt Consortium]
Keywords: | Anti-MTA3, Anti-KIAA1266, Anti-Metastasis-associated protein MTA3 |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: IHC-00424
Protein function: Functions as a general transcription factor playing a role in the process of transcriptional elongation. May mediate the reciprocal stimulatory effect of splicing on transcriptional elongation. In case of infection by HIV-1, it is up-regulated by the HIV-1 proteins NEF and gp120, acts as a cofactor...
Keywords: | Anti-Tat-SF1, Anti-HTATSF1, Anti-HIV Tat-specific factor 1 |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: IHC-00425
ATP-binding cassette sub-family F member 2 (ABCF2) belongs to the adenosine-triphosphate-binding cassette (ABC) family of transporters. ABC transporters are categorized into seven subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and white. ABCF2 is a member of the GCN20 subfamily. Unlike other ABC family members,...
Keywords: | Anti-ABCF2, Anti-HUSSY-18, Anti-Iron-inhibited ABC transporter 2, Anti-ATP-binding cassette sub-family F member 2 |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: IHC-00426
Protein function: Acts both as a regulator of telomere function and as a transcription regulator. Involved in the regulation of telomere length and protection as a component of the shelterin complex (telosome). In contrast to other components of the shelterin complex, it is dispensible for telomere capping and does...
Keywords: | Anti-hRap1, Anti-DRIP5, Anti-PP8000, Anti-TERF2IP, Anti-RAP1 homolog, Anti-TRF2-interacting telomeric protein 1,... |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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