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Antikörper Treffer 1
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Name/Antigen KLON WIRT TYP ISOTYP SPEZ. REAKT. FORMAT ANWENDUNG HERSTELLER KAT # MENGE PREIS










Anti-​EZH2 (Enhancer of Zeste Homolog 2, Histone-​lysine N-​methyltransferase EZH2, ENX1, ENX-​1, KMT6, KMT6A, Lysine N-​methyltransferase 6, MGC9169)
11C1032 Rabbit
> sec. Ab
Mab IgG
human, monkey, mouse, rat
Erklärungen der Abkürzungen ansehen.
purified WB
IP
IHC
IFErklärungen der Abkürzungen ansehen.
USBio
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E9085-​02D.100

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100 µl

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Anti-EZH2 (Enhancer of Zeste Homolog 2, Histone-lysine N-methyltransferase EZH2, ENX1, ENX-1, KMT6, KMT6A, Lysine N-methyltransferase 6, MGC9169)


Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-​EZH2 complex, which methylates 'Lys-​9' and 'Lys-​27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-​, di-​ and trimethylate 'Lys-​27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Compared to EZH2-​containing complexes, it is more abundant in embryonic stem cells and plays a major role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation. The PRC2/EED-​EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-​EZH2 complex include HOXC8, HOXA9, MYT1, CDKN2A and retinoic acid target genes. [The UniProt Consortium]
Immunogen: Synthetic peptide corresponding to residues surrounding Arg354 of human Ezh2.


Datenblatt ansehen

Kat #: E9085-02D.100


Menge:
100 µl

Buy Bulk


Preis:
510 €

UniProt ID: Q15910 (Protein knowledgebase)
Geninformationen: GeneID 2146

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Schlagworte:
EC=2.1.1.43, Anti-​Enhancer of zeste homolog 2, antibody, antibodies, Antikörper

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