Kontakt 0800-2466651 DE | EN Merkliste Login Warenkorb

Suche
zurück

Anti-DKK1, clone 2H2

ART NR.: Pro-20325 (100 µl)

Hersteller: ProMab

Datenblatt

Anwendungen: WB, ELISA

Format: ascites

Klon: 2H2

Wirt: Mouse

Isotyp: IgG2b

Reaktivität: human

Immunogen: Purified recombinant fragment of DKK1 expressed in E. coli.

UniProt ID: O94907
Suche mit UniProt ID

Geninformationen: GeneID 22943

Schlagworte: Anti-SK, Anti-DKK1, Anti-Dkk-1, Anti-hDkk-1, Anti-Dickkopf-1, Anti-Dickkopf-related protein 1

100 µl

226 €

In Warenkorb aufnehmen


Bemerkungen: Ascitic fluid containing 0.03% sodium azide. Protein function: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero- posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. [The UniProt Consortium]

Die Preise für Antikörper verstehen sich exkl. Versandkosten, eventuell anfallender Kühlmittelpauschale sowie der jeweils geltenden Mehrwertsteuer.



 


Forschungsprodukte im Fokus

 

Produkte

Service

Company

€ 10 Gutschein sichern