- Search results for Cay16611
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14 products were found matching "Cay16611"!
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Item number: Cay16666-1
Monocrotaline is a natural 11-membered macrocyclic pyrrolizidine alkaloid used in an animal model of pulmonary hypertension. It is metabolized by cytochrome P450 3A4 in the liver to monocrotaline pyrrole. Administration of monocrotaline or its metabolite monocrotaline pyrrole to rats causes progressive lung injury...
Keywords: | Crotaline, MCT, NSC 28693,... |
Application: | Pulmonary hypertension inducer |
CAS | 315-22-0 |
MW: | 325.4 D |
From 84.00€
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Item number: Cay11116-1
Mouse anti-c-myc IgG clone 9E10 (EQKLISEEDL) to DyLight(R) 550 Antibody: Mouse monoclonal anti-c-myc Clone: 9E10 Antigen: EQKLISEEDL Isotype: IgG1 Dye: DyLight(R) 550 Excitation max. lambda: 562 nm Emission max. lambda: 576 nm Uses: Flow cytometry, fluorescence-activated cell sorting, microscopy, and protein...
Application: | IF |
Host: | Mouse |
488.00€
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Item number: Cay11611-5
JWH 122 is a synthetic cannabinoid (CB) that displays high affinities for both the central CB1 receptor (Ki = 0.69 nM) and the peripheral CB2 receptor (Ki = 1.2 nM). JWH 122 N-(4-pentenyl) analog is structurally related to JWH 122, differing only by the presence of a terminal double bond on the acyl chain. This...
Keywords: | JWH 022 4-methylnaphthyl analog, MAM2201 N-(4-pentenyl) analog,... |
Application: | Analytical reference standard, Structural JWH 122 analog |
CAS | 1445577-68-3 |
MW: | 353.5 D |
From 291.00€
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Item number: Cay16111-25
5-Methylcytidine is a modified nucleoside derived from 5-methylcytosine and is a minor constituent of RNA as well as DNA for certain organisms. Roughly one to two residues of 5-methylcytidine occur in every 1,000 RNA residues. It has been used in epigenetics research, especially in studies involving DNA methylation...
Keywords: | NSC 363933, 5-methyl-cytidine |
Application: | DNA methylation studies |
CAS | 2140-61-6 |
MW: | 257.2 D |
From 54.00€
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Item number: Cay16614-1
SET domain-containing protein 8 (SETD8) is a methyltransferase that selectively monomethylates histone H4 at lysine residue 20 (H4K20), an event proven to have an important role in chromatin structure and transcriptional activation. It is also a regulator of p53, mono-methylating lysine 382 of the tumor suppressor....
Keywords: | Cdk4 Inhibitor III, Cyclic-dependent Kinase 4 Inhibitor III, SPS812,... |
Application: | SETD8 inhibitor |
CAS | 265312-55-8 |
MW: | 284.3 D |
From 44.00€
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Item number: Cay16615-1
BVT 948 is a noncompetitive, cell-permeable inhibitor of protein tyrosine phosphatases (PTP, IC50s = 0.09-1.7 µM). It facilitates the oxidation of the catalytic cysteine residue by hydrogen peroxide. Similarly, it inhibits redox-sensitive cytochrome P450 (CYP) isoforms, including CYP2C19 and CYP2D6, with IC50 values...
Keywords: | 4-hydroxy-3,3-dimethyl-2H-benz[g]indole-2,5(3H)-dione |
Application: | Noncompetitive, cell-permeable protein tyrosine phosphatase inhibitor |
CAS | 39674-97-0 |
MW: | 241.2 D |
From 43.00€
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Item number: Cay16618-1
Bupivacaine is a sodium channel blocker and local anesthetic. It inhibits sodium currents in rat dorsal horn neurons in a concentration-dependent manner and inhibits synaptic transmission in rat sympathetic ganglia, increasing the firing threshold when used at a concentration of 200 nM. Bupivacaine (10 µM) blocks...
Keywords: | 1-butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide |
Application: | Sodium influx blocker |
CAS | 38396-39-3 |
MW: | 288.4 D |
From 43.00€
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Item number: Cay16619-1
TGF-beta is a cell growth and differentiation factor that has roles in cancer, fibrosis, and numerous other pathologies. TGF-beta signals through two receptor tyrosine kinases, TGF-betaRI and TGF-betaRII. SD 208 is a potent inhibitor of TGF-betaRI kinase (EC50 = 48 nM) that has minimal or no effect at a variety of...
Keywords: | TGF-beta RI Kinase Inhibitor V, 2-(5-chloro-2-fluorophenyl)-N-4-pyridinyl-4-pteridinamine |
Application: | TGFBR1 inhibitor |
CAS | 627536-09-8 |
MW: | 352.8 D |
From 50.00€
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Item number: Cay16361-1
3,4-Methylenedioxy Pyrovalerone (3,4-MDPV, Cay-10684) is a central nervous system stimulant that has been widely abused. 3,4-Methylenedioxy-alpha-pyrrolidinohexanophenone (3,4-MDPHP) is an analog of 3,4-MDPV that differs only by the addition of a single carbon to the alkyl chain. The physiological and toxicological...
Keywords: | 3,4-MDPHP, 3,4-MD-alpha-PHP, 1-(1,3-benzodioxol-5-yl)-2-(1-pyrrolidinyl)-1hexanone, monohydrochloride |
Application: | Analytical reference standard, 3,4-MDPV analog |
CAS | 24622-61-5 |
MW: | 325.8 D |
From 280.00€
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Item number: Cay16621-1
MitoTEMPO is a mitochondria-targeted superoxide dismutase mimetic that possesses superoxide and alkyl radical scavenging properties. This compound combines the antioxidant piperidine nitroxide TEMPO with the lipophilic cation triphenylphosphonium, which allows it to pass through lipid bilayers and accumulate in...
Keywords: | 2,2,6,6-tetramethyl-4-[[2-(triphenylphosphonio)acetyl]amino]-1-piperidinyloxy, monochloride, monohydrate |
Application: | Mitochondria-targeted superoxide dismutase mimetic |
CAS | 1569257-94-8 |
MW: | 528 D |
From 43.00€
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Item number: Cay16761-1
AS-1842856 is a potent inhibitor of forkhead box class O transcription factor 1 (FoxO1, IC50 = 33 nM in HepG2 cells). Inhibition of FoxO1-mediated transactivation with AS-1842856 leads to a dose-dependent decrease in expression of glucose-6 phosphatase (G6Pase) and phosphoenolpyruvate carboxykinase (PEPCK) mRNA and...
Keywords: | FOXO1 Inhibitor, 5-amino-7-(cyclohexylamino)-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid |
Application: | Foxo1 Inhibitor |
CAS | 836620-48-5 |
MW: | 347.4 D |
From 42.00€
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Item number: Cay16261-1
The Ras family of small GTPases (H-Ras, K-Ras, and N-Ras) function as molecular switches, cycling between a GTP-bound active state and a GDP-bound inactive state, to turn on downstream Raf protein kinases. This initiates complex signaling pathways involved in cell growth, differentiation, and apoptosis. Mutations...
Keywords: | N-(3-chloro-4-methylphenyl)-2-[2,6-dinitro-4-(trifluoromethyl)phenyl]-hydrazinecarbothioamide |
Application: | Ras inhibitor |
CAS | 436133-68-5 |
MW: | 449.8 D |
From 50.00€
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