2 products were found matching "C8453-10"!
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Vicriviroc (maleate)
Item number: Cay28453-10
Vicriviroc is a chemokine (C-C motif) receptor 5 (CCR5) antagonist (Ki = 2.5 nM). It selectively inhibits CCR5 over M1 and M2 muscarinic acetylcholine receptors (Kis = >10,000 nM for both) and human-ether-a-go-go (hERG) potassium channels (IC50 = 5.8 µM). Vicriviroc decreases chemotaxis induced by chemokine (C-C...
| Keywords: | SCH 417690,... |
| Application: | CCR5 antagonist, Antiviral |
| CAS | 599179-03-0 |
| MW: | 649.7 D |
From 115.00€
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NASPM (hydrochloride)
Item number: Cay18453-10
NASPM is a synthetic analog of Joro spider toxin that blocks GluR2-lacking, Ca2+-permeable AMPA receptors. The blocking effect of NASPM on these receptors is use and voltage-dependent. At -60 mV, NASPM can suppress current responses in kainate-induced type II neurons (which are typified by strong inward...
| Keywords: | 1-Naphthylacetyl spermine, N-(3-((4-((3-aminopropyl)amino)butyl)amino)propyl)-2-(naphthalen-1-yl)acetamide, trihydrochloride |
| Application: | AMPA receptor blocker |
| CAS | 1049731-36-3 |
| MW: | 479.9 D |
From 34.00€
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