122 products were found matching "C7850-19C"!

C4-binding protein is a plasma protein with a molecular weight of 500000 and consists of 6 , chains. Its concentration in serum is about 250ug/ml. It is one of the inhibitors of the , complement activation system. The protein combines up to six molecules of C4b at or near , the C2 combining site and is thus...

Applications: , Suitable for use in ELISA, Immunoelectrophoresis and Single and Double Radial Immunodiffusion. Other applications not tested. Recommended Dilution: Immunoelectrophoresis: 2ml plasma or equivalent against 120ml antiserum, Double Radial Immunodiffusion: Use a rosette arrangement with 10ml antiserum in...

There are three variants of the Complement Component 4 Binding Protein (C4bp), composed of alpha and beta chains. The predominant form is a 570kD complex of 7 alpha chains and 1 beta chain. The other complexes formed are a 530kD homoheptamer of alpha chains or a 500kD complex of 6 alpha chains and 1 beta chain. C4bp...

The C2 component of human complement is a single-chain polypeptide with a molecular , weight of 110000. It is present in plasma in an average concentration of 25 µg/ml. The , activated form of C2 combines with the activated C4 to form a complex with C3-convertase , activity in the classical pathway of complement...

Applications:, Immunohistochemistry: (frozen)- 1:50-1:100 (direct), Optimal working dilutions to be determined by researcher., , Immunohistochemistry: Recommended positive control tissue: Human skin.

Human C4c produced in Human plasma having a molecular mass of 210kD. It interacts with C1 and C2 to form C3 convertase of the classic activation pathway. Systemic lupus erythematosus (SLE) is often associated with congenital C4 deficiency. Reduced levels of components of the classic pathway (C1, C2, C4, C3) are...

Human Complement component 3, C3 (alternative names include acylation-stimulating protein (ASP) C3 is encoded by gene located 19p13.3-p13.2. Because C3, C4, and C5 are strikingly similar suggesting a common evolutionary origin. C3 is an acute phase reactant. Synthesis of C3, a glycoprotein, is induced during acute...

Human Complement component 3, C3 (alternative names include acylation-stimulating protein (ASP) C3 is encoded by gene located 19p13.3-p13.2. Because C3, C4, and C5 are strikingly similar suggesting a common evolutionary origin. C3 is an acute phase reactant. Synthesis of C3, a glycoprotein, is induced during acute...

Human Complement component 3, C3 (alternative names include acylation-stimulating protein (ASP) C3 is encoded by gene located 19p13.3-p13.2. Because C3, C4, and C5 are strikingly similar suggesting a common evolutionary origin. C3 is an acute phase reactant. Synthesis of C3, a glycoprotein, is induced during acute...

Human Complement component 3, C3 (alternative names include acylation-stimulating protein (ASP) C3 is encoded by gene located 19p13.3-p13.2. Because C3, C4, and C5 are strikingly similar suggesting a common evolutionary origin. C3 is an acute phase reactant. Synthesis of C3, a glycoprotein, is induced during acute...

In the course of complement activation the C3a receptor functions as the cell surface receptor for the anaphylatoxin C3a, the C-terminal 77aa cleavage product of the alpha chain of C3, but not for C3a-desArg. All cellular responses to C3a are specifically mediated by interactions with the membrane bound C3a...

C3 is the most abundant complement protein in guinea pig serum. Its biological function strongly resembles that of C3 in man and other laboratory animal species. It has a central role in the activation system being common in both pathways. Activation of C3 is achieved by specific limited proteolysis resulting in...