Anti-Caspase 3

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A303-657A-T	10 µl (10 µg)		-		2 - 8 business days*		164.00€
A303-657A	100 µl (100 µg)		-		2 - 8 business days*		588.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

Protein function: Involved in the activation cascade of caspases responsible for apoptosis... more

Close menu

Product information "Anti-Caspase 3"

Protein function: Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-, -Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop- helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage. [The UniProt Consortium]

Keywords:	Anti-CASP3, Anti-CPP32, EC=3.4.22.56
Supplier:	Bethyl Laboratories
Supplier-Nr:	A303-657A

Properties

Application:	WB, IP, IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: gorilla, chinese hamster)
Immunogen:	Synthetic peptide. The epitope recognized by A303-657A maps to a region between residue 1 and 50 of human Caspase 3, apoptosis-related cysteine peptidase using the numbering given in entry NP_004337.2 (GeneID 836).
Format:	Antigen Affinity Purified