CLPP (ATP-dependent Clp protease proteolytic subunit) belongs to the peptidase family S14. CLPP cleaves peptides in various proteins in a process that requires ATP hydrolysis. CLPP, the catalytic core of the Clp proteolytic complex, is widely involved in many cellular processes via the regulation of intracellular...

CLPP is a conserved prokaryotic and eukaryotic ATP-dependent Serine S14 protease that hydrolyzes misfolded proteins into small peptides in the presence of ATP and magnesium. CLPP of Bacillus subtilis is induced by heat shock or general stress conditions. It plays an essential role in stress survival and growth at...