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Anti-Chk2, NT, (Checkpoint Kinase 2, Rad 53)

Item number: C4201-05.100

The p53 tumor-suppressor gene integrates numerous signals that control cell life and death. Several novel molecules involved in p53 signaling, including CHK2 (1), p53R2 (2), p53AIP1 (3), Noxa (4), PIDD (5), and PID/MTA2 (6), were recently discovered. The checkpoint kinase CHK2 is the mammalian homologue of yeast...

Keywords:	Anti-CDS1, Anti-hCds1, Anti-CHEK2, EC=2.7.11.1, Anti-Hucds1, Anti-Cds1 homolog, Anti-Checkpoint kinase 2, Anti-CHK2...
Application:	ELISA, WB
Host:	Rabbit
Species reactivity:	human, mouse, rat

644.00€ *

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Anti-CHK2 (Serine/Threonine-protein Kinase Chk2, Cds1,...

Item number: C4201-05H.100

CHK2, a protein kinase that is activated in response to DNA damage, is involved in cell cycle arrest.Mapped on 22q12.1, CHK2 has a potential regulatory region rich in SQ and TQ aa pairs. It regulates BRCA1 function after DNA damage by phosphorylating serine-988 of BRCA11. Additionally, CHK2 can be modified by...

Application:	IHC, WB
Host:	Rabbit
Species reactivity:	human, mouse, rat

606.00€ *

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