Anti-CD8-alpha (mouse, clone 53-6, R-PE conjugated

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ANC-260-050	120 tests		-		3 - 9 business days*		383.00€

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CD8 identifies cytotoxic/suppressor T cells that interact with MHC Class I bearing targets. CD8... more

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Product information "Anti-CD8-alpha (mouse, clone 53-6, R-PE conjugated"

CD8 identifies cytotoxic/suppressor T cells that interact with MHC Class I bearing targets. CD8 is thought to play a role in the process of T cell mediated killing. CD8-alpha chains binds to Class I MHC molecules alpha-3 domains. Defects in CD8A are a cause of familial CD8 deficiency [MIM:608957]. Familial CD8 deficiency is a novel autosomal recessive immunologic defect characterized by absence of CD8 cells, leading to recurrent bacterial infections.

Keywords:	Anti-CD8a, Anti-Cd8a, Anti-Lyt2, Anti-T-cell surface glycoprotein Lyt-2, Anti-T-cell surface glycoprotein CD8 alpha chain
Supplier:	Ancell
Supplier-Nr:	260-050

Properties

Application:	FC, ELISA
Antibody Type:	Monoclonal
Clone:	53-6
Conjugate:	Phycoerythrin
Host:	Rat
Species reactivity:	mouse
Immunogen:	murine thymocytes/splenocytes
Format:	Purified