Anti-CD49e (Fibronectin Receptor alpha, FNRA, Integrin alpha 5, ITGA5, Very Late Activation Protein

Anti-CD49e (Fibronectin Receptor alpha, FNRA, Integrin alpha 5, ITGA5, Very Late Activation Protein
Item number Size Datasheet Manual SDS Delivery time Quantity Price
C2405-02F6.500 500 µg - -

3 - 19 business days*

614.00€
 
CD49e is a 135kD protein, also known as a5 integrin or VLA-5 alpha chain. It is a member of the... more
Product information "Anti-CD49e (Fibronectin Receptor alpha, FNRA, Integrin alpha 5, ITGA5, Very Late Activation Protein"
CD49e is a 135kD protein, also known as a5 integrin or VLA-5 alpha chain. It is a member of the integrin family, expressed on thymocytes, splenic B cells, activated T cells, and mast cells. CD49e associates with CD29 (integrin beta1 chain) to form the fibronectin receptor (VLA-5). CD49e plays a critical role in both adhesion and T cell costimulation. The primary ligand for CD49e/CD29 (VLA-5) is fibronectin. This antibody has been shown to partially block CD49e mediated interactions. It has also been observed that plate-bound C2405-02F6 antibody enhances IgE mediated degranulation and that in vivo injection of this antibody, in combination with anti-CD49d and anti-CD61 antibodies, blocks passive cutaneous anaphylaxis. Applications: Suitable for use in Flow Cytometry and Immunoprecipitation. Other applications not tested. Recommended Dilution: Flow Cytometry: <0.25ug/10e6 cells in 100ul volume, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-VLA-5, Anti-Integrin alpha-F, Anti-Integrin alpha-5, Anti-Integrin alpha-5 heavy chain, Anti-Integrin alpha-5 light chain, Anti-CD49 antigen-like family member E, Anti-Fibronectin receptor subunit alpha
Supplier: United States Biological
Supplier-Nr: C2405-02F6

Properties

Application: FC, IP
Antibody Type: Monoclonal
Clone: HMa5-1
Conjugate: No
Host: Hamster
Species reactivity: mouse, rat
Immunogen: Affinity-purified mouse VLA-5 protein (a5b1, CD49e/CD29)
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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