27 products were found matching "C2549-29C"!

CD301 is a 38kD cell surface protein that is otherwise known as macrophage galactose N-acetylgalactosamine lectin (MGL) or dendritic cell asialoglycoprotein (DC-ASGPR). , In mice, CD301 is predominantly expressed on mature macrophages found associated with a wide range of connective tissues including macrophages in...

CD301 is a 38kD single chain surface glycoprotein and is found on murine mature macrophages in the connective tissue neighboring epithelia of e.g. salivary glands, capsule of lymph nodes, thymus and various other organs. CD301 is present on the surface of connective tissue macrophages and their precursor cells in...

CD274 is expressed constitutively on macrophages and dendritic cells, and is induced on activated T-cells, B-cells, endothelial cells and epithelial cells in response to Interferons alpha, beta and gamma. CD274 is reported to possess dual functions, inhibition of activated effector T cells and co-stimulation of...

CD273 is a 42kD member of the B7 family, otherwise known as B7-dendritic cell (B7-DC), or programmed death ligand-2 (PD-L2). The expression of CD273 is restricted to a subpopulation of dendritic cells (DCs), and DCs and macrophages that have been stimulated with interferon gamma, GM-CSF or IL-4. CD273 has been...

CD273 is a 42kD member of the B7 family, otherwise known as B7-dendritic cell (B7-DC), or programmed death ligand-2 (PD-L2). The expression of CD273 is restricted to a subpopulation of dendritic cells (DCs), and DCs and macrophages that have been stimulated with interferon gamma, GM-CSF or IL-4. CD273 has been...

Functions as an inhibitory receptor that plays a constitutive negative regulatory role on cytolytic function of natural killer (NK) cells, B-cells and T-cells. Activation by Tyr phosphorylation results in recruitment and activation of the phosphatases PTPN6 and PTPN11. It also reduces the increase of intracellular...

B7-H1, also known as PD-L1 and CD274, is a 50kD type I transmembrane protein in the B7 family. B7-H1 contains one Ig-like C2-type domain and one Ig-like V-type domain. It is constitutively expressed in several tissues and is upregulated on various tumors and activated dendritic cells, macrophages, and B cells. B7-H1...

CD273 is a single-pass type 1 membrane protein belonging to the immunoglobulin receptor superfamily, and is a ligand for CD279 (PD-1). CD273 is highly expressed in the tissues of the heart, liver, lung, placenta and pancreas. It is expressed in dendritic cells, and its expression can be induced on inflammatory...

B7-H1, also known as PD-L1 and CD274, is a 50kD type I transmembrane protein belonging to the B7 family. B7-H1 contains one Ig-like C2-type domain and one Ig-like V-type domain. It is constitutively expressed in several tissues and is up-regulated on various tumors and activated dendritic cells, macrophages, and B...

Molecular Structure: , A soluble fusion protein consisting of the murine CD8 alpha leader sequence, the mature extracellular (224aa) domain of human CD274 fused to murine IgG2a Fc + hinge (233aa). muCD8 apha signal peptide residual amino acids+ linker: (1) kpqapelrgsas , CD274 mature EC: (224aa):...

Applications: , Suitable for use in Flow Cytometry and Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are...

CD274, also known as B7-H1 and PD-1L, is a cell surface glycoprotein which is a member of the B7 family of co-stimulatory molecules. CD274 is expressed constitutively on macrophages and dendritic cells, and is induced on activated T-cells, B-cells, endothelial cells and epithelial cells in response to Interferons...