18 products were found matching "C2446-50"!

Endoglin is an endothelial homodimeric membrane antigen containing the tripeptide sequence RGD which is a recognition motif for adhesion receptors of the integrin family. CD105 is a Type I transmembrane protein and exists as an O-and N-glycosylated homodimer. Endoglin is a TGF beta-binding glycoprotein that is most...

CD105 (Endoglin, gp160, TGF beta1,3 Receptor) is a disulfide-linked type II transmembrane homodimer that is predominantly expressed on vascular endothelial cells. It is also found on pre-erythroblasts, macrophages and lymphoid and myeloid leukemic cells. Both mouse and human CD105 exhibit > 70% sequence homology in...

CD105/endoglin is a disulfide-linked type II transmembrane homodimer that is predominantly expressed on vascular endothelial cells. It is also found on pre-erythroblasts, macrophages and lymphoid and myeloid leukemic cells. Both mouse and human CD105 exhibit > 70% sequence homology in their cytoplasmic domains with...

Human CD105 (endoglin) is a homodimeric membrane glycoprotein virtually restricted to endothelial cells, and present on some leukemia cells and minor subsets of bone marrow cells. CD105 binds to TGF-b1 and b3 with high affinity. Applications: Suitable for use in Flow Cytometry and Immunohistochemistry. Other...

Applications:, Suitable for use in Flow Cytometry, Immunohistochemistry (frozen), Immunoprecipitation, and Westen Blot. Other applications not tested. Recommended Dilution: Flow Cytometry: 1:10-1:20, 10ul labels 10e6 cells in 100ul, Optimal dilutions to be determined by the researcher. Storage and Stability: May be...

CD105, also known as Endoglin, is a homodimeric type I transmembrane glycoprotein associated primarily with vascular endothelium. It binds TGF-beta1 and TGF-beta3 efficiently and forms a complex with the TGF-b signaling receptors, TGF-b receptors I and II. CD105 plays important roles in angiogenesis and...

CD105 (26-176 a.a.) or Endoglin or GP160 is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells, activated macrophages, fibroblasts, and smooth muscle cells. It exists as an O- and N-glycosylated homodimer of 180kD. Up-regulation of endoglin expression has been demonstrated...

Human CD105 (endoglin) is a homodimeric membrane glycoprotein virtually restricted to endothelial cells, and present on some leukemia cells and minor subsets of bone marrow cells. CD105 binds to TGF-b1 and b3 with high affinity. Antibody will augment binding of TGF-b1 to CD105 expressing leukemia cells,...

Human CD105 (endoglin) is a homodimeric membrane glycoprotein virtually restricted to endothelial cells, and present on some leukemia cells and minor subsets of bone marrow cells. CD105 binds to TGF-1 and 3 with high affinity. Applications: Suitable for use in Flow Cytometry and Immunohistochemistry. Other...

Endoglin (ENG, CD105) is an auxiliary receptor for the TGF-Beta receptor complex, functioning in related signaling pathways (1,2). Endoglin is a transmem-brane protein that exists as a disulfide-linked homodimer. It is mainly expressed in vascular and connective tissues and in endothelial and stromal cells....

CD105 (26-176 a.a.) or Endoglin or GP160 is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells, activated macrophages, fibroblasts, and smooth muscle cells. It exists as an O- and N-glycosylated homodimer of 180kD. Up-regulation of endoglin expression has been demonstrated...

Endoglin (CD105) is a 90kD type I transmembrane glycoprotein of the zona pellucida (ZP) family of proteins (1-3). Endoglin and betaglycan/TbRIII are type III receptors for TGF beta superfamily ligands, sharing 71% aa identity with within the transmembrane (TM) and cytoplasmic domains. Endoglin is highly expressed on...